PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
about
Turning off AKT: PHLPP as a drug targetSuppression of survival signalling pathways by the phosphatase PHLPPAbsence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle.Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output.Amino acid-induced impairment of insulin sensitivity in healthy and obese rats is reversible.Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophyAberrant expression of PHLPP1 and PHLPP2 correlates with poor prognosis in patients with hypopharyngeal squamous cell carcinomaPleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE ExposureLower expression of PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1) association with poor prognosis of gastric cancerDiacylglycerol kinase δ modulates Akt phosphorylation through pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2)Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.FANCI is a negative regulator of Akt activation.Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1)Exploiting p70 S6 kinase as a target for ovarian cancer.The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function.PHLPP phosphatases as a therapeutic target in insulin resistance-related diseases.PHLPPing through history: a decade in the life of PHLPP phosphatases.Oncogenic suppression of PHLPP1 in human melanoma.Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1.PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells.The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling.Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells.Loss expression of PHLPP1 correlates with lymph node metastasis and exhibits a poor prognosis in patients with gastric cancer.A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.Biochemical and cellular properties of insulin receptor signalling.PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) Regulates G-protein coupled Receptor Kinase 5 (GRK5) induced Cardiac Hypertrophy in vitro.The impact of phosphatases on proliferative and survival signaling in cancer.
P2860
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P2860
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@ast
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en-gb
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@nl
type
label
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@ast
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en-gb
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@nl
prefLabel
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@ast
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en-gb
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@nl
P2093
P2860
P356
P1476
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth
@en
P2093
Jianyu Liu
Micheal D Schmidt
Payton D Stevens
Tianyan Gao
P2860
P304
P356
10.1128/MCB.05799-11
P407
P577
2011-12-01T00:00:00Z