HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro
about
The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cellsRegulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA bindingThe homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequencesInteraction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signalingThe PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressorsThe homeobox gene Hex induces T-cell-derived lymphomas when overexpressed in hematopoietic precursor cellsThe homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiationAnalysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesisPRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.Molecular and developmental biology of the hemangioblastThe role of placental homeobox genes in human fetal growth restriction.Hhex Is Necessary for the Hepatic Differentiation of Mouse ES Cells and Acts via Vegf Signaling.Regulation and function of homeodomain proteins in the embryonic and adult vascular systems.PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate.The dual roles of homeobox genes in vascularization and wound healing.PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin.MS-818 accelerates mobilization of endothelial progenitor cells and differentiation to endothelial cells.Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism.
P2860
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P2860
HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro
description
2003 nî lūn-bûn
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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
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2003年论文
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name
HEX acts as a negative regulat ...... in endothelial cells in vitro
@ast
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en-gb
HEX acts as a negative regulat ...... in endothelial cells in vitro
@nl
type
label
HEX acts as a negative regulat ...... in endothelial cells in vitro
@ast
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en-gb
HEX acts as a negative regulat ...... in endothelial cells in vitro
@nl
prefLabel
HEX acts as a negative regulat ...... in endothelial cells in vitro
@ast
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en-gb
HEX acts as a negative regulat ...... in endothelial cells in vitro
@nl
P2093
P921
P1476
HEX acts as a negative regulat ...... in endothelial cells in vitro
@en
P2093
Hiroki Miyashita
Hitoshi Niwa
Mayumi Abe
Shoichi Kokubun
Tohru Yamazaki
Tomowaki Nakagawa
Yasufumi Sato
P356
10.1161/01.ATV.0000052670.55321.87
P407
P577
2003-02-01T00:00:00Z