The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
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The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) familyADAMTS-12 metalloprotease is necessary for normal inflammatory responseRegulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulinThe metalloproteinase ADAMTS1: a comprehensive review of its role in tumorigenic and metastatic pathways.Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells.ADAMTS-12: a multifaced metalloproteinase in arthritis and inflammationThe t(14,15) in mouse strain CBA/CaH-T(14;15)6Ca/J causes a break in the ADAMTS12 geneGenetic diversity, linkage disequilibrium and selection signatures in chinese and Western pigs revealed by genome-wide SNP markers.Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profilingDownregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.5p13.3p13.2 duplication associated with developmental delay, congenital malformations and chromosome instability manifested as low-level aneuploidy.Emerging Roles of ADAMTSs in Angiogenesis and Cancer.ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.ADAMTS6 suppresses tumor progression via the ERK signaling pathway and serves as a prognostic marker in human breast cancer.Adamts18 deficiency promotes colon carcinogenesis by enhancing β-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer.The role of ADAMTSs in arthritisThe roles of ADAMTS in angiogenesis and cancer.ADAMTS4 and its proteolytic fragments differentially affect melanoma growth and angiogenesis in mice.Osteopontin can decrease the expression of Col-II and COMP in cartilage cells in vitro.New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent.Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15Placental Ras Regulates Inflammation Associated with Maternal ObesityAnalysis of porcine body size variation using re-sequencing data of miniature and large pigs
P2860
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P2860
The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@ast
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en-gb
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@nl
type
label
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@ast
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en-gb
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@nl
prefLabel
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@ast
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en-gb
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@nl
P2093
P50
P921
P356
P1476
The ADAMTS12 metalloproteinase ...... pendent ERK signalling pathway
@en
P2093
Angela Moncada-Pazos
María Llamazares
Santiago Cal
P304
P356
10.1242/JCS.005751
P407
P577
2007-10-15T00:00:00Z