Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. - Wikidata - awgldk - TriplyDB

Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.

Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.

http://www.wikidata.org/entity/Q34682013

about

The syndrome of microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) is caused by mutations in ADAMTS18 A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.A highly recurrent RPS27 5'UTR mutation in melanoma.Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling ADAMTS-18: a metalloproteinase with multiple functions Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.Delving into somatic variation in sporadic melanoma.Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.ADAMTS-18 in the host tissues exerts little effect on breast tumor progress in a murine 4T1 breast cancer model Emerging Roles of ADAMTSs in Angiogenesis and Cancer.Exploiting the curative potential of adoptive T-cell therapy for cancer.Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.Sp1 is necessary for gene activation of Adamts17 by estrogen.ERBB4 mutation analysis: emerging molecular target for melanoma treatment.Identification of a thrombin cleavage site and a short form of ADAMTS-18.New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.RNAi screening of the human colorectal cancer genome identifies multifunctional tumor suppressors regulating epithelial cell invasion Differentially regulated ADAMTS1, 8, 9, and 18 in pancreas adenocarcinoma.Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15

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Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.

http://www.wikidata.org/entity/Q34682013

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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type

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Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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prefLabel

Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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Mutational and functional anal ...... as a novel driver in melanoma.

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1541-7786.MCR-10-0262

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Molecular Cancer Research

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Mutational and functional anal ...... as a novel driver in melanoma.

@en

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Alfredo Molinolo

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Cristina G Viloria

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Isabel Cardenas-Navia

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Jeffrey E Gershenwald

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Jimmy C Lin

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Michael A Davies

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Pedro Cruz

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Steven A Rosenberg

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Todd D Prickett

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Xiaomu Wei

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P2860

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity

The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway

Structural and functional alterations of FLT3 in acute myeloid leukemia

Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

Consed: a graphical tool for sequence finishing

The consensus coding sequences of human breast and colorectal cancers

The genomic landscapes of human breast and colorectal cancers

High frequency of mutations of the PIK3CA gene in human cancers

Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9

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1513-1525

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10.1158/1541-7786.MCR-10-0262

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11

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8

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Carlos López Otín

Yardena Samuels

NISC Comparative Sequencing Program

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2010-10-13T00:00:00Z

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21047771

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