Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
about
Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulinA model of anthrax toxin lethal factor bound to protective antigen.Molecular details of cAMP generation in mammalian cells: a tale of two systemsBacillus anthracis edema factor substrate specificity: evidence for new modes of actionToxin-based therapeutic approachesRatcheting up protein translocation with anthrax toxinA 1.3-Å Structure of Zinc-bound N-terminal Domain of Calmodulin Elucidates Potential Early Ion-binding StepStructure of androcam supports specialized interactions with myosin VICerthrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereusThe Structure of Mlc Titration Factor A (MtfA/YeeI) Reveals a Prototypical Zinc Metallopeptidase Related to Anthrax Lethal FactorLethal and edema toxins in the pathogenesis of Bacillus anthracis septic shock: implications for therapyMolecular motions as a drug target: mechanistic simulations of anthrax toxin edema factor function led to the discovery of novel allosteric inhibitors.Empirical valence bond simulations of the chemical mechanism of ATP to cAMP conversion by anthrax edema factor.Novel inhibitors of anthrax edema factor.The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor.Cross-reactivity of anthrax and C2 toxin: protective antigen promotes the uptake of botulinum C2I toxin into human endothelial cellsNew developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Structural basis of anthrax edema factor neutralization by a neutralizing antibodyInteractions of anthrax lethal factor with protective antigen defined by site-directed spin labelingActivation of the edema factor of Bacillus anthracis by calmodulin: evidence of an interplay between the EF-calmodulin interaction and calcium binding.Mapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factorAnthrax edema factor toxicity is strongly mediated by the N-end ruleAB toxins: a paradigm switch from deadly to desirableEffects of 39 Compounds on Calmodulin-Regulated Adenylyl Cyclases AC1 and Bacillus anthracis Edema FactorMouse monoclonal antibodies to anthrax edema factor protect against infection.Electrostatic ratchet in the protective antigen channel promotes anthrax toxin translocation.Diminished but Not Abolished Effect of Two His351 Mutants of Anthrax Edema Factor in a Murine ModelNew insights into the pathogenesis and treatment of anthrax toxin-induced shock.Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta.A journey in science: promise, purpose, privilege.Calmodulin mediates the Ca2+-dependent regulation of Cx44 gap junctions.Dynamics and energetics: a consensus analysis of the impact of calcium on EF-CaM protein complexNovel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.The adenylyl cyclase activity of anthrax edema factor.Structural diversity of calmodulin binding to its target sites.Interaction with adenylate cyclase toxin from Bordetella pertussis affects the metal binding properties of calmodulin.Cell entry and cAMP imaging of anthrax edema toxinThe Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.
P2860
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P2860
Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Calcium-independent calmodulin ...... hanism of anthrax edema factor
@nl
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@ast
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en-gb
type
label
Calcium-independent calmodulin ...... hanism of anthrax edema factor
@nl
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@ast
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en-gb
prefLabel
Calcium-independent calmodulin ...... hanism of anthrax edema factor
@nl
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@ast
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en
Calcium-independent calmodulin ...... anism of anthrax edema factor.
@en-gb
P2093
P2860
P356
P1433
P1476
Calcium-independent calmodulin ...... hanism of anthrax edema factor
@en
P2093
Natalia L Zhukovskaya
Yuequan Shen
P2860
P304
P356
10.1038/SJ.EMBOJ.7600574
P407
P577
2005-02-17T00:00:00Z