The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.
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Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology toolsBacillus anthracis edema factor substrate specificity: evidence for new modes of actionCellular and physiological effects of anthrax exotoxin and its relevance to disease.Passive Immunotherapy Protects against Enteric Invasion and Lethal Sepsis in a Murine Model of Gastrointestinal AnthraxThe Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection.Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussisBoth lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain.Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route.Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunityThe Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapseBordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokinesTissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection.New insights into the biological effects of anthrax toxins: linking cellular to organismal responsesToxins-useful biochemical tools for leukocyte research.T cell targeting by anthrax toxins: two faces of the same coin.The myriad roles of cyclic AMP in microbial pathogens: from signal to swordAnthrax lethal toxin and the induction of CD4 T cell immunity.The virulence factors of Bordetella pertussis: talented modulators of host immune response.Anthrax Vaccine Precipitated induces Edema Toxin-neutralizing, Edema Factor-specific antibodies in human recipients.Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells.Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate inductionElevated cyclic AMP Inhibits Mycobacterium tuberculosis-stimulated T cell IFN-γ Secretion through type I Protein Kinase A.A bivalent protein r-PB, comprising PA and BclA immunodominant regions for comprehensive protection against Bacillus anthracis.Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.
P2860
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P2860
The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.
description
2009 nî lūn-bûn
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2009 թվականի մարտին հրատարակված գիտական հոդված
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2009年の論文
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name
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@ast
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@en
type
label
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@ast
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@en
prefLabel
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@ast
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@en
P2093
P2860
P1433
P1476
The adenylate cyclase toxins o ...... ll antigen receptor signaling.
@en
P2093
Cesare Montecucco
Cosima T Baldari
Irene Zornetta
Marisa Benagiano
Nagaja Capitani
Silvia Rossi Paccani
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000325
P577
2009-03-06T00:00:00Z