A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.
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Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin ICharcot-Marie-Tooth disease and intracellular trafficProtein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancerThe dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophagesCIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.Dynamin 2 potentiates invasive migration of pancreatic tumor cells through stabilization of the Rac1 GEF Vav1Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons.Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulationARAP1 association with CIN85 affects epidermal growth factor receptor endocytic traffickingIQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liverInhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion.Lipid droplet breakdown requires dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes.Control of MT1-MMP transport by atypical PKC during breast-cancer progression.The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis.HBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation.A screen for X-linked mutations affecting Drosophila photoreceptor differentiation identifies Casein kinase 1α as an essential negative regulator of wingless signaling.CD2AP regulates SUMOylation of CIN85 in podocytes.CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies.Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling.Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics.MS/MS-based strategies for proteomic profiling of invasive cell structures.Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.The significance of dynamin 2 expression for prostate cancer progression, prognostication, and therapeutic targeting.Identification of a pivotal endocytosis motif in c-Met and selective modulation of HGF-dependent aggressiveness of cancer using the 16-mer endocytic peptide.Where EGF receptors transmit their signals.Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation.Dynamin A, Myosin IB and Abp1 Couple Phagosome Maturation to F-Actin BindingHuman Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency
P2860
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P2860
A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A Dyn2-CIN85 complex mediates ...... tion of late endosomal budding
@nl
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@ast
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en-gb
type
label
A Dyn2-CIN85 complex mediates ...... tion of late endosomal budding
@nl
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@ast
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en-gb
prefLabel
A Dyn2-CIN85 complex mediates ...... tion of late endosomal budding
@nl
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@ast
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en-gb
P2093
P2860
P356
P1433
P1476
A Dyn2-CIN85 complex mediates ...... ion of late endosomal budding.
@en
P2093
Barbara Schroeder
Daniel Billadeau
Mark A McNiven
Shaun G Weller
P2860
P304
P356
10.1038/EMBOJ.2010.190
P407
P577
2010-08-13T00:00:00Z