Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.
about
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machineryA Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.Dab2 links CIN85 with clathrin-mediated receptor internalizationLigand-induced downregulation of TrkA is partly regulated through ubiquitination by CblCIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptorsA tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulationDistinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional ImplicationsCharacterization of multiple multivesicular body sorting determinants within Sna3: a role for the ubiquitin ligase Rsp5.Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes.The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167.Non-traditional functions of ubiquitin and ubiquitin-binding proteinsA Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeletonSH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complexThe ubiquitin-like protein monoclonal nonspecific suppressor factor beta conjugates to endophilin II and regulates phagocytosisDifferential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interactionARAP1 association with CIN85 affects epidermal growth factor receptor endocytic traffickingIdentification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalizationAlix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.The ORF3 protein of hepatitis E virus delays degradation of activated growth factor receptors by interacting with CIN85 and blocking formation of the Cbl-CIN85 complex.Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.Regulation of lck degradation and refractory state in CD8+ cytotoxic T lymphocytesThe basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis.The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signalingSignaling-mediated control of ubiquitin ligases in endocytosis.Receptors of anthrax toxin and cell entry.Endocytosis and intracellular trafficking of ErbBs.Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes.The role of the ubiquitin/proteasome system in cellular responses to radiation.EH and UIM: endocytosis and more.CD2AP regulates SUMOylation of CIN85 in podocytes.E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation.Coiled-coil domains enhance the membrane association of Salmonella type III effectors.Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family.CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies.EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate.The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor
P2860
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P2860
Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cbl-directed monoubiquitinatio ...... d degradation of EGF receptors
@nl
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@ast
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en-gb
type
label
Cbl-directed monoubiquitinatio ...... d degradation of EGF receptors
@nl
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@ast
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en-gb
prefLabel
Cbl-directed monoubiquitinatio ...... d degradation of EGF receptors
@nl
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@ast
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en-gb
P2860
P356
P1476
Cbl-directed monoubiquitinatio ...... degradation of EGF receptors.
@en
P2093
Iwona Szymkiewicz
Noriaki Shimokawa
P2860
P304
12191-12196
P356
10.1073/PNAS.192462299
P407
P577
2002-09-06T00:00:00Z