EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy
about
Transplantation of specific human astrocytes promotes functional recovery after spinal cord injuryPrecursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injuryMsh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in miceAstrocytes are central in the pathomechanisms of vanishing white matterAstrocytes: biology and pathologyPoor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter diseaseA yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM diseaseDevelopmental splicing deregulation in leukodystrophies related to EIF2B mutationsClinical and neuroimaging findings of Cree leukodystrophy: a retrospective case series.MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells.Evaluation of the endoplasmic reticulum-stress response in eIF2B-mutated lymphocytes and lymphoblasts from CACH/VWM patientsDefective glial maturation in vanishing white matter disease.A point mutation in translation initiation factor eIF2B leads to function--and time-specific changes in brain gene expression.The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases.CSF N-glycan profiles to investigate biomarkers in brain developmental disorders: application to leukodystrophies related to eIF2B mutationsGlia Disease and Repair-RemyelinationAstrocytes are an early target in osmotic demyelination syndromeBrain connexins in demyelinating diseases: therapeutic potential of glial targetsGlial progenitor cell-based treatment and modeling of neurological diseaseCHOP and the endoplasmic reticulum stress response in myelinating gliaDelayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons.Astrocyte phenotypes and their relationship to myelination.Myelination: do astrocytes play a role?ASTROCYTES: EMERGING STARS IN LEUKODYSTROPHY PATHOGENESIS.Astrocyte regulation of CNS inflammation and remyelination.Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in vanishing white matter disease.Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders.Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms.Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.Progenitor cell-based treatment of glial disease.Natural history of adult-onset eIF2B-related disorders: a multi-centric survey of 16 cases.Stratification of astrocytes in healthy and diseased brain.Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study.Characterization of mature rat oligodendrocytes: a proteomic approach.Axonal abnormalities in vanishing white matter.Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro.Update on leukodystrophies
P2860
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P2860
EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@ast
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en-gb
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@nl
type
label
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@ast
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en-gb
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@nl
prefLabel
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@ast
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en-gb
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
EIF2B5 mutations compromise GF ...... ng white matter leukodystrophy
@en
P2093
Carlos Torres
Christoph Pröschel
David Gass
Eric Richfield
Jörg Dietrich
Margot Mayer-Pröschel
Mark Noble
Michelle Lacagnina
P2860
P2888
P304
P3181
P356
10.1038/NM1195
P407
P577
2005-03-01T00:00:00Z
P6179
1033439209