about
RAG1 core and V(D)J recombination signal sequences were derived from Transib transposonsEvolution of the RAG1-RAG2 locus: both proteins came from the same transposonVprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelitySUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.The recombination activation gene 1 (Rag1) is expressed in a subset of zebrafish olfactory neurons but is not essential for axon targeting or amino acid detection.Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair.Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1Recombination-activating gene proteins: more regulation, pleaseThe taming of a transposon: V(D)J recombination and the immune systemAutoubiquitylation of the V(D)J recombinase protein RAG1A WW-like module in the RAG1 N-terminal domain contributes to previously unidentified protein-protein interactionsElucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid bindingRequirement for ubiquitin conjugation and 26S proteasome activity at an early stage in V(D)J recombinationMobilization of RAG-generated signal ends by transposition and insertion in vivoV(D)J recombination.The bounty of RAGs: recombination signal complexes and reaction outcomes.New concepts in the regulation of an ancient reaction: transposition by RAG1/RAG2.Role of RAG1 autoubiquitination in V(D)J recombination.RAG1-mediated ubiquitylation of histone H3 is required for chromosomal V(D)J recombination.Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.Ku70 is stabilized by increased cellular SUMOKaryopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase.RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2.Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences.Role of recombination activating genes in the generation of antigen receptor diversity and beyond.Ubiquitination events that regulate recombination of immunoglobulin Loci gene segments.Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision.Full-length RAG-2, and not full-length RAG-1, specifically suppresses RAG-mediated transposition but not hybrid joint formation or disintegration.V(D)J Recombination: Mechanism, Errors, and Fidelity.Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures.New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination.V(D)J Recombination Exploits DNA Damage Responses to Promote Immunity.Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice.RNase H As Gene Modifier, Driver of Evolution and Antiviral Defense.Structure and biochemical function of a prototypical Arabidopsis U-box domain.Correlation between recombinase activating gene 1 ubiquitin ligase activity and V(D)J recombination.Epigenetic regulation of antigen receptor gene rearrangement.
P2860
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P248
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@ast
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en-gb
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@nl
type
label
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@ast
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en-gb
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@nl
prefLabel
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@ast
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en-gb
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
The RAG1 N-terminal domain is an E3 ubiquitin ligase
@en
P2093
Moshe Sadofsky
Vyacheslav Yurchenko
P2860
P3181
P356
10.1101/GAD.1058103
P407
P577
2003-03-01T00:00:00Z