Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
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Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells.Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis.Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC levelResveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ.Synergistic effects of combined treatment with histone deacetylase inhibitor suberoylanilide hydroxamic acid and TRAIL on human breast cancer cells.N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.Towards novel paradigms for cancer therapy.Naturally occurring, tumor-specific, therapeutic proteins.Death receptors as targets in cancerMultifunctional adamantane derivatives as new scaffolds for the multipresentation of bioactive peptides.Clinically applicable human adipose tissue-derived mesenchymal stem cells delivering therapeutic genes to brainstem gliomas.Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction.Multimerization of an apoptogenic TRAIL-mimicking peptide by using adamantane-based dendrons.TRAIL-NP hybrids for cancer therapy: a review.HYDRAmers: design, synthesis and characterization of different generation novel Hydra-like dendrons based on multifunctionalized adamantane.Antibody covalent immobilization on carbon nanotubes and assessment of antigen binding.An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor 5.Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5: conformational analysis, dimerisation and consequences for receptor activation.Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels.Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized.Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells.Comparative binding to DR4 and DR5 receptors of TRAIL and BNNTs/PAHE/mPEG-DSPE/TRAIL nanoparticles.Structural Insight for Roles of DR5 Death Domain Mutations on Oligomerization of DR5 Death Domain-FADD Complex in the Death-Inducing Signaling Complex Formation: A Computational Study.Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes.Luminescent Iridium Complex-Peptide Hybrids (IPHs) for Therapeutics of Cancer: Design and Synthesis of IPHs for Detection of Cancer Cells and Induction of Their Necrosis-Type Cell Death
P2860
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P2860
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@ast
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en-gb
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@nl
type
label
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@ast
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en-gb
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@nl
prefLabel
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@ast
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en-gb
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@nl
P2093
P50
P3181
P1433
P1476
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
@en
P2093
Alexandre Morizot
Christophe Pardin
Jean-Paul Briand
Julien Beyrath
Marie-Charlotte Lechner
Miriam Wendland
Olivier Micheau
Valeria Pavet
Wolfgang Maison
P304
P3181
P356
10.1158/0008-5472.CAN-09-2889
P407
P577
2010-02-01T00:00:00Z