about
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activityStructure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approachStructure-based design of short peptide ligands binding onto the E. coli processivity ringDifferential modes of peptide binding onto replicative sliding clamps from various bacterial originsThe proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complexSolution structure of a retro-inverso peptide analogue mimicking the foot-and-mouth disease virus major antigenic site. Structural basis for its antigenic cross-reactivity with the parent peptideThe anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycansMelanoma peptide MART-1(27-35) analogues with enhanced binding capacity to the human class I histocompatibility molecule HLA-A2 by introduction of a beta-amino acid residue: implications for recognition by tumor-infiltrating lymphocytes.Molecular Recognition within the Cavity of a Foldamer Helix Bundle: Encapsulation of Primary Alcohols in Aqueous Conditions.Mimicking helical antibacterial peptides with nonpeptidic folding oligomers.1,3,5-Triazepane-2,6-diones as structurally diverse and conformationally constrained dipeptide mimetics: identification of malaria liver stage inhibitors from a small pilot library.In silico-guided target identification of a scaffold-focused library: 1,3,5-triazepan-2,6-diones as novel phospholipase A2 inhibitors.Sequencing of oligourea foldamers by tandem mass spectrometry.Shaping quaternary assemblies of water-soluble non-peptide helical foldamers by sequence manipulation.Proline-rich antimicrobial peptides targeting protein synthesis.A retro-inverso peptide corresponding to the GH loop of foot-and-mouth disease virus elicits high levels of long-lasting protective neutralizing antibodies.N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signallingStabilized helical peptides: overview of the technologies and therapeutic promises.Ligand dimerization programmed by hybridization to study multimeric ligand-receptor interactions.SUBPOL: a novel SUcrose-Based Polymer support for solid-phase peptide synthesis and affinity chromatography applications.Helical Oligourea Foldamers as Powerful Hydrogen Bonding Catalysts for Enantioselective C-C Bond-Forming Reactions.N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy.Proteolytically Stable Foldamer Mimics of Host-Defense Peptides with Protective Activities in a Murine Model of Bacterial Infection.A cell-penetrating foldamer with a bioreducible linkage for intracellular delivery of DNA.Native ESI Mass Spectrometry Can Help to Avoid Wrong Interpretations from Isothermal Titration Calorimetry in Difficult Situations.Multimerization of an apoptogenic TRAIL-mimicking peptide by using adamantane-based dendrons.Genes of the N-methylglutamate pathway are essential for growth of Methylobacterium extorquens DM4 with monomethylamine.Effect of replacing main-chain ureas with thiourea and guanidinium surrogates on the bactericidal activity of membrane active oligourea foldamers.Small multivalent architectures mimicking homotrimers of the TNF superfamily member CD40L: delineating the relationship between structure and effector function.Cooperativity in the interaction of synthetic CD40L mimetics with CD40 and its implication in cell signaling.Solid-phase synthesis of CD40L mimetics.Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5: conformational analysis, dimerisation and consequences for receptor activation.Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels.tert-Butyl 3-oxo-2-oxa-5-aza-bicyclo-[2.2.1]heptane-5-carboxyl-atePseudopeptide TASP inhibitors of HIV entry bind specifically to a 95-kDa cell surface protein.5-(3,4-Dimethoxybenzyl)-7-isopropyl-1,3,5-triazepane-2,6-dione acetonitrile solvate refined using a multipolar atom model.Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone.Anion-macrodipole interactions: self-assembling oligourea/amide macrocycles as anion transporters that respond to membrane polarization.
P50
Q24297502-FA458699-0E8D-4A79-BA99-0D6DF78AFDD2Q27631636-9638553C-CE91-442B-B266-D68D3892909AQ27668061-CC861459-9B99-4EC1-872F-37C856C075D8Q27694822-1D4A06C9-36DD-415E-B413-DB959E699197Q27700868-E6AFF6A8-8FCC-44D2-AB80-D948D01E4292Q27766742-95E35C57-0084-45D5-A20E-7B2A695462F8Q28372900-FA610B58-129C-43D6-982B-D548B47B476CQ30938087-65407387-4D0D-4D29-BDCC-6EA37F62B811Q31165681-FDCF0232-0818-43F0-A7D5-E8B6BF636A01Q33244397-A056EC73-8D64-4315-A296-77B15C268DABQ33254926-D1FABCA6-84B1-4155-95C2-153C46B25A62Q33265867-DCB71B04-E713-46A3-ADE5-3F54111525C2Q34582756-FBFCAD73-0F99-4CDF-837E-40BABE3BD1CCQ35817201-38172B00-4585-4A67-8F9D-E05AD242368EQ36379116-7EE6A94C-353C-4BEE-A056-23C65A98B134Q36822090-98ADB5CB-63A5-4D1F-86E0-A344F340ABA4Q37691437-01D60848-FC66-49F6-BC1E-8491C89BB932Q37706093-C985CE18-55A7-41F9-8BB0-F2FECA09C542Q37745184-86D755DF-1822-4A65-8764-48C98576C2E1Q38014489-B8BB8506-B623-4054-A694-E0BF7A8A68A1Q38340746-A4E66D52-90FB-4AF4-9573-56FAC7BAFCF7Q38348620-DF2EE0D7-5BC0-4180-9BC2-C2EE82ABC868Q38645997-2709AE59-D9DA-4B83-BBA4-E780C6C3E7A7Q38755747-419F9A0D-BA1C-457B-AABA-A8E026BD8B9AQ38830888-91B72143-939B-4141-AC96-E2BBFB847564Q38846070-4F7E3CD5-C8E9-4D23-B1F5-9914743CDCCBQ39106323-0E33286F-6CC1-40A1-A724-E86808D8E826Q39226253-A87A138E-2E66-4553-A6AC-EE784DC8936FQ39539564-E8D86E7B-BDAE-417A-9E4B-16CF6AD02E03Q40144015-C673C50F-F8E2-4E87-BE11-F9E897EE2AEDQ40164236-6EED7FFD-E5AF-44C2-86B3-B664D966CAB9Q40167391-22D05F54-3B65-4BF9-B784-BB90053473CEQ40294213-8FD96345-B1D4-4329-A004-EA9EF392AE67Q41714576-5DF4C120-2594-40BE-859B-F93DB70F3DF8Q41778655-B36EE714-21B7-464B-B7A4-2DEC34389555Q42128241-530FF50D-11BD-461B-8E6E-B39B03022664Q42550973-693E3E33-F3C1-44D1-8A82-C20E0AAEB870Q43044909-AF83A5C3-7E9C-418E-84B5-AE3A26F229B5Q43231197-C61B632B-1096-4121-9408-59B3AD89ED19Q43251853-3B0DF6DA-10FD-4B27-951C-10EFDC651E98
P50
description
hulumtues
@sq
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Gilles Guichard
@ast
Gilles Guichard
@en
Gilles Guichard
@es
Gilles Guichard
@nl
Gilles Guichard
@sl
type
label
Gilles Guichard
@ast
Gilles Guichard
@en
Gilles Guichard
@es
Gilles Guichard
@nl
Gilles Guichard
@sl
prefLabel
Gilles Guichard
@ast
Gilles Guichard
@en
Gilles Guichard
@es
Gilles Guichard
@nl
Gilles Guichard
@sl
P214
P1053
I-3858-2016
P106
P108
P1153
7003509379
P21
P214
P31
P3829
P496
0000-0002-2584-7502
P735
P7859
viaf-173043062