Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition
about
FAK in cancer: mechanistic findings and clinical applicationsFAK acts as a suppressor of RTK-MAP kinase signalling in Drosophila melanogaster epithelia and human cancer cellsMonitoring the cytoskeletal EGF response in live gastric carcinoma cellsPhosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changesInhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivoTetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cellsMET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryosAllosteric regulation of focal adhesion kinase by PIP₂ and ATP.FAK is required for the assembly of podosome rosettesVEGF-induced vascular permeability is mediated by FAK.Phospholipid binding to the FAK catalytic domain impacts function.Disrupting the scaffold to improve focal adhesion kinase-targeted cancer therapeuticsMoving beyond VEGF for anti-angiogenesis strategies in gynecologic cancerpHocal adhesion kinase regulation is on a FERM foundation.Tivantinib (ARQ197) in hepatocellular carcinoma.Exploiting receptor tyrosine kinase co-activation for cancer therapy.EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications.Focal adhesion kinase signaling in unexpected places.Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.Signaling by METMET activates PTK2 signalingPhosphorylation of Drebrin and Its Role in Neuritogenesis.MET phosphorylates PTK2SRC phosphorylates PTK2Physiological Signaling and Structure of the HGF Receptor MET.Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions
P2860
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P2860
Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@ast
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en-gb
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@nl
type
label
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@ast
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en-gb
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@nl
prefLabel
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@ast
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en-gb
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@nl
P2093
P2860
P356
P1433
P1476
Phosphorylation of focal adhes ...... rough relief of autoinhibition
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2010.398
P407
P577
2011-01-13T00:00:00Z
P5875
P6179
1040644499