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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome proteinMyotonic dystrophy protein kinase domains mediate localization, oligomerization, novel catalytic activity, and autoinhibitionCLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibitionRegulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibitionInsights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuityAutoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandemStructural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase.Structural analysis of autoinhibition in the Ras activator Son of sevenlessStructure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibitionAutoinhibition of the insulin-like growth factor I receptor by the juxtamembrane regionStructural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1Autoinhibition of human dicer by its internal helicase domainStructural basis for autoinhibition of ESCRT-III CHMP3Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domainStructural basis for ESCRT-III protein autoinhibitionAutoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.The alternatively spliced acid box region plays a key role in FGF receptor autoinhibitionA novel mechanism of P-type ATPase autoinhibition involving both termini of the proteinStructural basis for autoinhibition and phosphorylation-dependent activation of c-CblFunction of the N-terminus of zizimin1: autoinhibition and membrane targeting.Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 buddingStructural basis for the autoinhibition of focal adhesion kinaseAutoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.5-HT1A Receptor-Mediated Autoinhibition and the Control of Serotonergic Cell FiringAutoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alphaStructure of Gialpha1.GppNHp, autoinhibition in a galpha protein-substrate complexStructure of PAK1 in an autoinhibited conformation reveals a multistage activation switchStructural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylationCrystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibitionCrystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibitionStructural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane regionStructural analysis of the autoinhibition of Ets-1 and its role in protein partnershipsStructural basis for the autoinhibition of c-Abl tyrosine kinaseCatalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzymeCrystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivationCrystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding foldThe structural basis for autoinhibition of FLT3 by the juxtamembrane domainThe 2.7 A crystal structure of the autoinhibited human c-Fms kinase domainStructural basis for autoinhibition of Notch
P921
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P921
description
regulatory mechanism in biology
@en
name
autoinhibition
@en
type
label
autoinhibition
@en
prefLabel
autoinhibition
@en