A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity
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Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in manGeneralized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorderChrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changesDesign principles of nuclear receptor signaling: how complex networking improves signal transduction.A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressivThe human glucocorticoid receptor: molecular basis of biologic functionFamilial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation.Primary generalized familial and sporadic glucocorticoid resistance (Chrousos syndrome) and hypersensitivityRecent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor.Glucocorticoid receptor mutants demonstrate increased motility inside the nucleus of living cells: time of fluorescence recovery after photobleaching (FRAP) is an integrated measure of receptor function.Activated glucocorticoid receptor interacts with the INHAT component Set/TAF-Ibeta and releases it from a glucocorticoid-responsive gene promoter, relieving repression: implications for the pathogenesis of glucocorticoid resistance in acute undifferScreening for urinary biomarkers of steroid-resistant nephrotic syndrome in children.Structural Analysis on the Pathologic Mutant Glucocorticoid Receptor Ligand-Binding Domains.A novel point mutation in the DNA-binding domain (DBD) of the human glucocorticoid receptor causes primary generalized glucocorticoid resistance by disrupting the hydrophobic structure of its DBD.A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression.Characterization of a novel gain of function glucocorticoid receptor knock-in mouseBifunctional ligands allow deliberate extrinsic reprogramming of the glucocorticoid receptor.The Smad6-histone deacetylase 3 complex silences the transcriptional activity of the glucocorticoid receptor: potential clinical implications.Chrousos syndrome: from molecular pathogenesis to therapeutic management.Genetic variation in the glucocorticoid pathway involved in interindividual differences in the glucocorticoid treatment.Effects of parabens on adipocyte differentiation.Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features.Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease.A novel mutation of the hGR gene causing Chrousos syndrome.Primary generalized glucocorticoid resistance and hypersensitivity: the end-organ involvement in the stress response.Functional characterization of the hGRαT556I causing Chrousos syndrome.An unexpected, mild phenotype of glucocorticoid resistance associated with glucocorticoid receptor gene mutation case report and review of the literature.HIV Neuroinfection and Alzheimer's Disease: Similarities and Potential Links?
P2860
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P2860
A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A novel point mutation in the ...... ing transactivational activity
@ast
A novel point mutation in the ...... ing transactivational activity
@en
A novel point mutation in the ...... ing transactivational activity
@en-gb
A novel point mutation in the ...... ing transactivational activity
@nl
type
label
A novel point mutation in the ...... ing transactivational activity
@ast
A novel point mutation in the ...... ing transactivational activity
@en
A novel point mutation in the ...... ing transactivational activity
@en-gb
A novel point mutation in the ...... ing transactivational activity
@nl
prefLabel
A novel point mutation in the ...... ing transactivational activity
@ast
A novel point mutation in the ...... ing transactivational activity
@en
A novel point mutation in the ...... ing transactivational activity
@en-gb
A novel point mutation in the ...... ing transactivational activity
@nl
P2093
P921
P356
P1476
A novel point mutation in the ...... ing transactivational activity
@en
P2093
Anatoly Tiulpakov
Annaswamy Raji
George P Chrousos
Keith Zachman
Takamasa Ichijo
Tomoshige Kino
P304
P356
10.1210/JC.2004-1920
P407
P577
2005-03-15T00:00:00Z