Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
about
In vitro and in vivo characterization of highly purified human mesothelioma derived cellsMFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st CenturyDickkopf-1 promotes hyperglycemia-induced accumulation of mesangial matrix and renal dysfunction.β-Catenin transcriptional activity is minimal in canine osteosarcoma and its targeted inhibition results in minimal changes to cell line behaviour.Mouse models for cancer stem cell research.Epigenetic remodeling of chromatin architecture: exploring tumor differentiation therapies in mesenchymal stem cells and sarcomasMesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies.The genetic basis for inactivation of Wnt pathway in human osteosarcoma.A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patientsWnt/β-catenin expression does not correlate with serum alkaline phosphatase concentration in canine osteosarcoma patientsMesenchymal stem cell-derived microparticles: a promising therapeutic strategy.Hiwi mediated tumorigenesis is associated with DNA hypermethylationLocal mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiencyMesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment.CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2.The Wnt signaling pathway: implications for therapy in osteosarcoma.PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcomaMesenchymal stem cell transformation and sarcoma genesis.Histologic and genetic advances in refining the diagnosis of "undifferentiated pleomorphic sarcoma"Genomic signatures predict poor outcome in undifferentiated pleomorphic sarcomas and leiomyosarcomas.High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A.KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathwaysHuman ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.microRNAs, Gap Junctional Intercellular Communication and Mesenchymal Stem Cells in Breast Cancer Metastasis.Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model.A transgenic, mesodermal specific, Dkk1 mouse model recapitulates a spectrum of human congenital limb reduction defects.Solid tumor differentiation therapy - is it possible?Inflammatory malignant fibrous histiocytoma associated with leukemoid reaction or leukocytosis: a comprehensive review.Genetically engineered mouse models and human osteosarcoma.Targeting Wnt pathways in disease.A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signalingThe role of Dickkopf-1 in bone development, homeostasis, and diseaseMesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype.Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cellsMesenchymal stem cells as therapeutics.Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repairGene expression profiling for the investigation of soft tissue sarcoma pathogenesis and the identification of diagnostic, prognostic, and predictive biomarkers.An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity.
P2860
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P2860
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@ast
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en-gb
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@nl
type
label
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@ast
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en-gb
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@nl
prefLabel
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@ast
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en-gb
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@nl
P2093
P2860
P50
P3181
P356
P1476
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
@en
P2093
Carlos Cordon-Cardo
Igor Matushansky
Joslyn E Mills
Mark A Edgar
Nicholas D Socci
Tulio A Matos
P2860
P304
P3181
P356
10.1172/JCI31377
P407
P577
2007-11-01T00:00:00Z