RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
about
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombinationRNF4 interacts with both SUMO and nucleosomes to promote the DNA damage responseThe histone demethylase LSD1/KDM1A promotes the DNA damage responseUbc13: the Lys63 ubiquitin chain building machineWriters, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairChoreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear ArchitectureInterplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic StressReal Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand BreaksRole of Deubiquitinating Enzymes in DNA RepairA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work53BP1: pro choice in DNA repairDNA DSB repair pathway choice: an orchestrated handover mechanismExpression and functionality of histone H2A variants in cancerCrosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repairStructural basis for role of ring finger protein RNF168 RING domainRegulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligaseRepair of DNA Double-Strand Breaks in HeterochromatinHistone ubiquitylation and its roles in transcription and DNA damage responseUbiquitylation, neddylation and the DNA damage responseUSP51 deubiquitylates H2AK13,15ub and regulates DNA damage responseDouble strand break repair functions of histone H2AX53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.And-1 is required for homologous recombination repair by regulating DNA end resection.The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sitesSMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression.An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.ATM signalling and cancer.RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor RecruitmentThe TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage.Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damageGeneration of nonhydrolyzable ubiquitin-histone mimicsNucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.Cell biology of mitotic recombination.
P2860
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P2860
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@ast
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en-gb
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@nl
type
label
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@ast
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en-gb
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@nl
prefLabel
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@ast
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en-gb
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@nl
P2093
P921
P3181
P1433
P1476
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
@en
P2093
Elisabetta Citterio
Francesca Mattiroli
Joseph H A Vissers
Jurgen A Marteijn
Pauline Ikpa
Titia K Sixma
Willem J van Dijk
P304
P3181
P356
10.1016/J.CELL.2012.08.005
P407
P577
2012-09-14T00:00:00Z