An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.
about
Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairEctopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.Salient Features of Endonuclease Platforms for Therapeutic Genome EditingDistinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks.The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus.PRPF8 is important for BRCA1-mediated homologous recombination.ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair.RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repairRepeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements
P2860
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P2860
An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
An RNF168 fragment defective f ...... tion in BRCA1 deficient cells.
@en
type
label
An RNF168 fragment defective f ...... tion in BRCA1 deficient cells.
@en
prefLabel
An RNF168 fragment defective f ...... tion in BRCA1 deficient cells.
@en
P2093
P2860
P356
P1476
An RNF168 fragment defective f ...... tion in BRCA1 deficient cells.
@en
P2093
Diana A Yanez
Jeremy M Stark
Meilen C Muñoz
P2860
P304
P356
10.1093/NAR/GKU421
P407
P577
2014-05-14T00:00:00Z