Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release
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Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targetsTargeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7Methylation of the retinoblastoma tumor suppressor by SMYD2Molecular mechanisms underlying RB protein functionStructure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressorCrystal Structure of the Retinoblastoma Protein N Domain Provides Insight into Tumor Suppression, Ligand Interaction, and Holoprotein ArchitectureAn overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma proteinCrystal structure of the unliganded retinoblastoma protein pocket domainStructures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle controlGetting to S: CDK functions and targets on the path to cell-cycle commitmentExperimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for badE2f4 is required for normal development of the airway epitheliumQuantitative relation between intermolecular and intramolecular binding of pro-rich peptides to SH3 domains.Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780A comparative study of Whi5 and retinoblastoma proteins: from sequence and structure analysis to intracellular networks.Cell size checkpoint control by the retinoblastoma tumor suppressor pathwaySeparation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain.RSS1 regulates the cell cycle and maintains meristematic activity under stress conditions in rice.The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent mannerDevelopment of an accurate classification system of proteins into structured and unstructured regions that uncovers novel structural domains: its application to human transcription factors.Protein post-translational modifications: In silico prediction tools and molecular modeling.The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axisThe antiviral cytokine interferon-gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation.Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain bindingHuman papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.Autoactivation of the MDM2 E3 ligase by intramolecular interaction.Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein.Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics.Paradoxical instability-activity relationship defines a novel regulatory pathway for retinoblastoma proteins.Cyclin-dependent kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30·mSin3·HDAC transcriptional repressor complex.Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycleStructural insights into the mechanism of phosphoregulation of the retinoblastoma proteinThe high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.PRMT4-mediated arginine methylation negatively regulates retinoblastoma tumor suppressor protein and promotes E2F-1 dissociationSite-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity.Limited redundancy in phosphorylation of retinoblastoma tumor suppressor protein by cyclin-dependent kinases in acute lymphoblastic leukemiaRetinoblastoma protein modulates the inverse relationship between cellular proliferation and elastogenesisStructural mechanisms of DREAM complex assembly and regulation.Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency.
P2860
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P2860
Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structure of the Rb C-terminal ...... horylation-induced E2F release
@ast
Structure of the Rb C-terminal ...... horylation-induced E2F release
@en
Structure of the Rb C-terminal ...... horylation-induced E2F release
@nl
type
label
Structure of the Rb C-terminal ...... horylation-induced E2F release
@ast
Structure of the Rb C-terminal ...... horylation-induced E2F release
@en
Structure of the Rb C-terminal ...... horylation-induced E2F release
@nl
prefLabel
Structure of the Rb C-terminal ...... horylation-induced E2F release
@ast
Structure of the Rb C-terminal ...... horylation-induced E2F release
@en
Structure of the Rb C-terminal ...... horylation-induced E2F release
@nl
P2093
P921
P3181
P1433
P1476
Structure of the Rb C-terminal ...... horylation-induced E2F release
@en
P2093
Anne-Laure Gall
Nikola P Pavletich
Ning Zheng
Seth M Rubin
P304
P3181
P356
10.1016/J.CELL.2005.09.044
P407
P577
2005-12-16T00:00:00Z