Methylation of the retinoblastoma tumor suppressor by SMYD2
about
HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulatorEpigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral DeficitsOpen access chemical probes for epigenetic targetsThe functional diversity of protein lysine methylationAn unexpected journey: lysine methylation across the proteomeSMYD proteins: key regulators in skeletal and cardiac muscle development and functionRB1: a prototype tumor suppressor and an enigmaMolecular mechanisms underlying RB protein functionSmall-Molecule Ligands of Methyl-Lysine Binding ProteinsCrystal Structures of Histone and p53 Methyltransferase SmyD2 Reveal a Conformational Flexibility of the Autoinhibitory C-Terminal DomainStructure of Human SMYD2 Protein Reveals the Basis of p53 Tumor Suppressor MethylationHistone lysine methyltransferases as anti-cancer targets for drug discoveryThe selective activation of p53 target genes regulated by SMYD2 in BIX-01294 induced autophagy-related cell deathEvolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal SpeciesHistone-binding domains: strategies for discovery and characterization.Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis.Substrate and product specificities of SET domain methyltransferasesDNA damage signals through differentially modified E2F1 molecules to induce apoptosis.G1 arrest and differentiation can occur independently of Rb family function.SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancerPRMT4-mediated arginine methylation negatively regulates retinoblastoma tumor suppressor protein and promotes E2F-1 dissociationSelective inhibitors of protein methyltransferasesRegulation of p53 function by lysine methylation.Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.Genetic alterations of histone lysine methyltransferases and their significance in breast cancerTargeting protein lysine methylation and demethylation in cancers.LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.Overexpression of SMYD2 contributes to malignant outcome in gastric cancer.Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization.Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2.JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein.RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.Whole exome sequencing of microdissected splenic marginal zone lymphoma: a study to discover novel tumor-specific mutations.G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression.Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based ProteomicsCoordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication.A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation.
P2860
Q24297641-0C70CCD1-B10B-45C2-A7F6-6337341D3441Q26748876-4CF310F9-1A86-4FA7-9366-26A5A38CDFF8Q26781872-8D1B6E48-8527-45AB-AF19-2F11031C1ADDQ26853164-F1DB6B04-0D41-4D69-B72D-4CF69446BEB4Q26864659-589AA41C-D6CE-4F66-939C-B54136C31644Q26865167-12A28560-6F55-4FFD-A234-42D36C80B67CQ26866393-49823264-22B6-4751-AF5A-99227D57D37CQ27003956-529C0BA2-8EF6-4C25-8B60-E1FB778CAABAQ27667285-E9ACAACE-2A67-46CC-8F7D-8072B75D5655Q27670728-1771894B-6D83-4DA4-8E46-05EAEC367AE6Q27672574-7A4337DF-A06A-4F10-8F3D-3F4924A28773Q28076288-2521B951-1D58-4567-BEA3-174C97D2C9A8Q28542974-BA5B4D2D-407D-4718-9566-ACE97CE12B7DQ28645901-FB727280-E9D9-4828-A78A-4CC61FB47D46Q33905467-6B4566AA-5113-4462-810F-80289A5BC1F9Q34150501-25B8486F-F8AB-453B-9659-D72DBDF4999CQ34208487-8222FDCE-132D-4BEA-8B89-F012DE13B5ACQ34241750-30B91790-71D9-4FDF-B6B2-9F91A7AEADB8Q34317041-4AC940C9-34CC-4E44-9F11-01C52A1BD428Q34420873-770FBD05-BC9E-4C68-A801-09E31390C7E1Q34968529-85049E0F-789F-42DA-93A4-1897C254B648Q35135783-C04CBF59-3552-43C8-AB2B-EFEE46EDD5CAQ35149921-B4658C90-BC57-44FE-B1F9-FF24F91C8C51Q35214419-96AE512D-3760-4F64-AB39-DF40BEB5DCD4Q35237394-C1D919E3-A39D-481F-99F5-5F525454C5B0Q35273743-856467D5-79CB-45C2-B921-C16D913D2536Q35629831-036EBD68-2B54-48F0-8DB6-0409E63ACA52Q35662225-1120944E-75CC-4075-A806-639018E4E60FQ35677250-3360387F-56AB-4AC8-94F5-16A3C1D34572Q35740604-6E370713-694D-4953-83F0-FA246E2A3A9EQ35745144-080EB74B-B451-4A67-A75E-3543EE2EE35CQ35881815-BAA6924C-DA17-4586-96AE-ABAF661321FBQ36040610-CF7C6728-2BC0-4E75-9580-D79B09316819Q36088167-D5FD0BC1-4DFC-462C-AA7B-B314B90AB7F7Q36203511-E8E7591F-6FAB-4580-928D-84E8AD690027Q36690093-6C64195E-671E-43C7-B264-540E9639D399Q36745154-E9AB3FC0-6400-46E4-A066-614B0EAAFC30Q36783008-70152A0C-6EF8-42E2-8813-400597D7F3D3Q36833415-4E013146-4A41-4906-A97A-F82403918EF1Q36862579-08691FEF-F58D-4278-B422-0070C7EB82F5
P2860
Methylation of the retinoblastoma tumor suppressor by SMYD2
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Methylation of the retinoblastoma tumor suppressor by SMYD2
@ast
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en-gb
Methylation of the retinoblastoma tumor suppressor by SMYD2
@nl
type
label
Methylation of the retinoblastoma tumor suppressor by SMYD2
@ast
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en-gb
Methylation of the retinoblastoma tumor suppressor by SMYD2
@nl
prefLabel
Methylation of the retinoblastoma tumor suppressor by SMYD2
@ast
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en-gb
Methylation of the retinoblastoma tumor suppressor by SMYD2
@nl
P2093
P2860
P921
P3181
P356
P1476
Methylation of the retinoblastoma tumor suppressor by SMYD2
@en
P2093
Aaron Aslanian
John R Yates
Lisandra E West
Louis A Saddic
Seth M Rubin
P2860
P304
P3181
P356
10.1074/JBC.M110.137612
P407
P577
2010-11-26T00:00:00Z