PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation
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H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress responseThe formation and function of ER-endosome membrane contact sitesThe molecular rationale of Src inhibition in colorectal carcinomasEGF receptor trafficking: consequences for signaling and cancerA novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation.Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cellsTumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer TheranosticsTargeting PTPs with small molecule inhibitors in cancer treatmentProtein tyrosine phosphatase 1B expression contributes to the development of breast cancer.Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.Targeting the disordered C terminus of PTP1B with an allosteric inhibitorProstaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome.Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.CB₁ cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells.Targeting protein tyrosine phosphatases for anticancer drug discovery.Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530.Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1BFrequent amplification of PTP1B is associated with poor survival of gastric cancer patientsCsk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H2O2-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells.Signalling by protein phosphatases and drug development: a systems-centred view.Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Cell Transformation by PTP1B Truncated Mutants Found in Human Colon and Thyroid Tumors.Src, p130Cas, and Mechanotransduction in Cancer CellsIncreased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome.Phosphorylation at tyrosine 262 promotes GADD34 protein turnover.Novel role of ASC as a regulator of metastatic phenotype.Thiol-based redox switches in eukaryotic proteins.PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.PTP1B expression is an independent positive prognostic factor in human breast cancer.Association of PTP1B with Outcomes of Breast Cancer Patients Who Underwent Neoadjuvant Chemotherapy.PTP1B: a double agent in metabolism and oncogenesis.A model for phospho-caveolin-1-driven turnover of focal adhesions.IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling.Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer.The regulatory roles of phosphatases in cancer.Protein trafficking in colorectal carcinogenesis-targeting and bypassing resistance to currently applied treatments.Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells.Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma.
P2860
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P2860
PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
PTP1B contributes to the oncog ...... r cells through Src activation
@ast
PTP1B contributes to the oncog ...... r cells through Src activation
@en
PTP1B contributes to the oncog ...... r cells through Src activation
@nl
type
label
PTP1B contributes to the oncog ...... r cells through Src activation
@ast
PTP1B contributes to the oncog ...... r cells through Src activation
@en
PTP1B contributes to the oncog ...... r cells through Src activation
@nl
prefLabel
PTP1B contributes to the oncog ...... r cells through Src activation
@ast
PTP1B contributes to the oncog ...... r cells through Src activation
@en
PTP1B contributes to the oncog ...... r cells through Src activation
@nl
P2093
P3181
P1433
P1476
PTP1B contributes to the oncog ...... r cells through Src activation
@en
P2093
Donald J Fujita
Jeffrey D Bjorge
Shudong Zhu
P304
P3181
P356
10.1158/0008-5472.CAN-06-4338
P407
P577
2007-11-01T00:00:00Z