Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells
about
Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseThe E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulumGenome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyAdaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsWolfram Syndrome: Diagnosis, Management, and TreatmentThe Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for TreatmentEndoplasmic reticulum stress and type 2 diabetesEndoplasmic reticulum stress in the β-cell pathogenesis of type 2 diabetesXenobiotic perturbation of ER stress and the unfolded protein responseNeonatal diabetes: an expanding list of genes allows for improved diagnosis and treatmentRole of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram SyndromeNatural history of β-cell adaptation and failure in type 2 diabetesWolfram syndrome: new mutations, different phenotypeWolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response.Neuroimaging evidence of deficient axon myelination in Wolfram syndrome.Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.Congenital central diabetes insipidus and optic atrophy in a Wolfram newborn: is there a role for WFS1 gene in neurodevelopment?A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease.Endocrine Glands and Hearing: Auditory Manifestations of Various Endocrine and Metabolic Conditions.Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors.Autophagy, Endoplasmic Reticulum Stress and the Unfolded Protein Response in Intracerebral Hemorrhage.Decreased insulin secretion and increased risk of type 2 diabetes associated with allelic variations of the WFS1 gene: the Data from Epidemiological Study on the Insulin Resistance Syndrome (DESIR) prospective study.Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese populationNeuropeptide Y expression marks partially differentiated β cells in mice and humansGrandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscleRegulation of basal cellular physiology by the homeostatic unfolded protein responseTranscriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophyAtypical case of Wolfram syndrome revealed through targeted exome sequencing in a patient with suspected mitochondrial disease.Wolfram syndrome in the Japanese population; molecular analysis of WFS1 gene and characterization of clinical features.Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.Early brain vulnerability in Wolfram syndrome.Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegenerationA mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis.A calcium-dependent protease as a potential therapeutic target for Wolfram syndromeCentral nervous system PET-CT imaging reveals regional impairments in pediatric patients with Wolfram syndromeUPR, autophagy, and mitochondria crosstalk underlies the ER stress responseA WFS1 haplotype consisting of the minor alleles of rs752854, rs10010131, and rs734312 shows a protective role against type 2 diabetes in Russian patients.Impairment of visual function and retinal ER stress activation in Wfs1-deficient mice.
P2860
Q24293694-61DC7FA0-A453-4124-878B-1E685A7AAE4EQ24298474-FC0C44DB-7F19-45AE-BCCA-52B63E90BDDDQ26742051-17C76DCD-D416-4582-ACEA-0C07A3E81257Q26765956-ACA4C1E8-A792-40D7-877E-46FC971286F0Q26770241-CD155F69-3642-44E0-BB39-B2064D300D97Q26776377-919B50CE-C06C-499D-8F5D-2BFB349A1D63Q26864238-9B38ED45-4C9C-4084-A772-2846CEF1A273Q26864340-25C8CDEE-E613-405A-A385-F8C88637E2C2Q26998690-9FCA4C63-07A9-41FA-B2F0-EF7C5601A69FQ27013756-1FC7FA20-F733-48A1-BF2A-F93D8F78950DQ27342152-915071C0-CA2B-4C75-946D-F1751EB6E9E2Q28082002-F7905B8F-E821-422A-B025-2D3BEF3B34F9Q28478694-DE38C61A-275B-41BE-B033-493FD32958DAQ28589308-34A0238B-0EEE-402C-8D3A-08704E82BE45Q28593657-2578D2C0-869E-4D0B-A3A2-5E533EF24D93Q30390322-7FA7FBE0-7269-4513-A8C8-E9D9BC98A054Q30421540-25ED2298-036F-43A6-A982-A9A1E701B86CQ30855176-C3DADF8E-D303-4EB4-8191-71541465DE32Q33622482-32236DA1-B46A-43DA-82E8-E58E24BEA3CBQ33653691-4D55D97C-277F-42B4-A0A8-27C627CD1B40Q33697524-096886A6-2FBB-4682-BADE-55CFE699ED44Q33702937-3E21A123-F29B-4F41-9AC7-0CCC889470FEQ33726445-969402F2-FACF-4812-A4BE-F2DA09807199Q33762350-9A64BC98-446B-4B4A-B9D0-D15F53B2438FQ33787414-9CD9E229-22E8-4CAA-A862-31BF1F606C71Q33798117-57F689AB-BF84-4C3A-BC6B-73FD6699CACBQ33836210-C82C96F8-0246-45BC-8152-D2165BED84DAQ33886820-6F296BAC-4F4E-4719-B5B1-024FCDBF68CCQ34026175-ACB56C47-C91F-4491-B544-3F49504BDEB8Q34121020-C1EF13ED-CB91-4205-8983-1DB711C9F0CCQ34166073-C4A9BD1D-4FF2-4ACC-B15E-9E64FB2A9CF5Q34258755-2F8BFB27-B67E-434B-A42B-DA4104FAF120Q34336601-C933BC1E-CDDD-4BE5-B8BF-074635948258Q34451639-B1C7142E-9A7B-46A4-93F1-51996C60C344Q34596904-132C5E6F-0371-4906-8154-951ECD3C6C81Q34709034-3C620973-6C09-4A18-B16B-778B5132EE7BQ34776001-9C47562C-8B58-4704-B738-88256C1874F5Q35122358-B4E21A29-2CBD-4F64-9EE7-C6CC17B3785DQ35127946-DB759F95-570B-4B50-BC6C-4AD69100F802Q35167762-C6462D6C-A853-4B20-A33E-95A56AE90699
P2860
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@ast
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en-gb
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@nl
type
label
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@ast
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en-gb
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@nl
prefLabel
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@ast
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en-gb
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@nl
P2093
P2860
P921
P3181
P356
P1476
Wolfram syndrome 1 gene negati ...... ling in rodent and human cells
@en
P2093
Christine M Oslowski
Emiko Hayashi
Fumihiko Urano
Hisamitsu Ishihara
Kathryn L Lipson
M Alan Permutt
Rajarshi Ghosh
Shinsuke Ishigaki
Sonya G Fonseca
P2860
P304
P3181
P356
10.1172/JCI39678
P407
P577
2010-03-01T00:00:00Z