about
Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activityA Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replicationMechanism of cancer cell death induced by depletion of an essential replication regulatorCrystal structure of human CDC7 kinase in complex with its activator DBF4Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195Dual role of the Cdc7-regulatory protein Dbf4 during yeast meiosis.Identification of Mcm2 phosphorylation sites by S-phase-regulating kinasesA high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage responseDDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approachDrf1-dependent kinase interacts with Claspin through a conserved protein motif.Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replicationPhosphorylated Rad18 directs DNA polymerase η to sites of stalled replicationMiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.Eukaryotic MCM proteins: beyond replication initiation.Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.Cell cycle regulation of DNA replication.Dbf4: the whole is greater than the sum of its partsCdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpointRoles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities.Recent advances of pyrrolopyridines derivatives: a patent and literature review.3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation.Identification of stimulators and inhibitors of Cdc7 kinase in vitro.A synthetic human kinase can control cell cycle progression in budding yeast.Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition.Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts.Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1.Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognitionXenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest.Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities.Xenopus CDC7/DRF1 complex is required for the initiation of DNA replication.p53 gain-of-function mutations increase Cdc7-dependent replication initiation.Maturation-associated Dbf4 expression is essential for mouse zygotic DNA replication.Cdc7 is an active kinase in human cancer cells undergoing replication stress.
P2860
Q24648278-246F3EED-B785-4D2D-94A9-41899744D33CQ24800392-10F543EE-F10B-4B65-96E4-24F683D60E48Q27303672-234BB15E-F005-4D6D-8870-B40D09BF40D9Q27682804-0D4C1951-C408-42C6-805F-C51742F371EEQ27684195-26CDBF3E-032D-4DF7-B3FA-5C82F25B8F74Q27930214-4BF8EE15-831F-4F72-A1FE-BEACA4AE44A8Q28294583-406D0BE2-AFDC-442D-9040-8EB587547F62Q28539430-03FA5362-64D7-48A0-887F-5539FE13E68AQ28822095-714808DC-930C-485B-B183-331B9EF5244CQ33800164-BEC91BD9-DB6B-4CAD-BB33-3C0059DCDC7FQ34055919-CBCEFBF6-897B-4EBD-A33A-DE5EFC93E2B1Q34368618-A52238BC-03B4-48C6-8B34-4B7452C6DB62Q34476593-76E69AE0-9CC4-4302-8558-57FD5CD3980CQ35121210-CCE81E32-8442-44BD-B6A3-B92F019A4EBCQ35684975-72E00D25-8EDB-4174-A9F2-F6A8B638F198Q36187252-1EC5455C-FE09-4927-B72F-1784BEB28601Q36881426-AA12FC30-630B-48F8-BB54-33012D2034CBQ36906226-B0C0DE8A-7BD5-4E98-9085-3B8F8E8A91C3Q36923333-D3C45F77-F2AA-4450-8E8A-964C73178559Q37724141-04417233-92C8-4C34-B1D1-1B41D9A52B5CQ39074256-BD1340F0-5024-4D63-B700-14009A9D2441Q39514113-D2DDC294-4FD1-49C2-8FFC-D90BB3517A7BQ39949011-C9B7E9F6-D03D-40AF-A77D-AEC282BEE44EQ39987475-34CF9F4E-C145-4321-A127-D1BF7D88D617Q40976272-A452FFD6-6A06-4C05-8F44-B3BF5FF5D852Q40985225-C0E04509-B73F-455F-BE85-408B25F5F4A9Q41305957-6C02F81C-739A-4915-BE35-C68248CC4241Q41809632-EB356136-297A-435A-B597-0F53855B3468Q42136223-2AF56590-F319-4EA6-87D0-D33700C81B7CQ42773681-467BCACA-EB9F-40BA-B830-DCF0FA921BC2Q44277681-0522C026-1B9C-4403-91E9-0386D9B845C9Q47614531-F556AD80-4B76-4454-9B8F-FEA832DD013FQ48098026-F0037441-0790-4B69-94F8-BE1613C183DFQ48100871-CD761D23-65A7-46C2-9E5B-D5819ADFE301Q48592130-447D8F3C-84A3-4D69-8D88-49A5A3BBD347Q53591767-1340C08C-DCBF-4FDD-9FFB-D5D42CFF45F1
P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Drf1, a novel regulatory subunit for human Cdc7 kinase
@ast
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en-gb
Drf1, a novel regulatory subunit for human Cdc7 kinase
@nl
type
label
Drf1, a novel regulatory subunit for human Cdc7 kinase
@ast
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en-gb
Drf1, a novel regulatory subunit for human Cdc7 kinase
@nl
prefLabel
Drf1, a novel regulatory subunit for human Cdc7 kinase
@ast
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en-gb
Drf1, a novel regulatory subunit for human Cdc7 kinase
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Drf1, a novel regulatory subunit for human Cdc7 kinase
@en
P2093
Berthelsen J
Brotherton D
Mercurio C
Montagnoli A
Rialland M
Santocanale C
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF290
P407
P577
2002-06-01T00:00:00Z