3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

P2860

Q27684195-995E55D1-E6E8-4EE3-9783-43548EB0E682

P2860

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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Item

label

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

@en

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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P1476

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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P2093

Annette Walter

http://www.w3.org/2001/XMLSchema#string

Asha Yabannavar

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Christopher McBride

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Cynthia M Shafer

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Kent Wong

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Maureen McKenna

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Mika Lindvall

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Song Lin

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Thomas G Gesner

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P2860

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

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A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors

First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery

Functions of mammalian Cdc7 kinase in initiation/monitoring of DNA replication and development

Cdc7 inhibition reveals a p53-dependent replication checkpoint that is defective in cancer cells

Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases

Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex.

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720-723

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scholarly article

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10.1021/ML200029W

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2011-08-02T00:00:00Z

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24900258

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P932

4018153

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3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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P2860

P2860

3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932