The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles
about
The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAPMyotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathiesMutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucomaPhosphoinositides: tiny lipids with giant impact on cell regulationLoss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafishCaenorhabditis elegans myotubularin MTM-1 negatively regulates the engulfment of apoptotic cellsAAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasisZebrafish MTMR14 is required for excitation-contraction coupling, developmental motor function and the regulation of autophagy.The role of PI3P phosphatases in the regulation of autophagyDrosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functionsMTM1 mutation associated with X-linked myotubular myopathy in Labrador Retrievers.Membrane traffic and muscle: lessons from human diseaseWnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells.Disease-related myotubularins function in endocytic traffic in Caenorhabditis elegans.Endosomal targeting of the phosphoinositide 3-phosphatase MTMR2 is regulated by an N-terminal phosphorylation site.The myotubularin family of lipid phosphatases in disease and in spermatogenesisPhosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in miceClass II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization moduleEndosomal phosphoinositides and human diseases.A natural history study of X-linked myotubular myopathy.Gene replacement rescues severe muscle pathology and prolongs survival in myotubularin-deficient mice and dogs.PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membranePI(3;5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane
P2860
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P2860
The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2002 թվականի օգոստոսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@ast
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en-gb
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@nl
type
label
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@ast
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en-gb
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@nl
prefLabel
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@ast
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en-gb
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@nl
P2093
P50
P1476
The PtdIns3P phosphatase myotu ...... ucible plasma membrane ruffles
@en
P2093
Francois Blondeau
Jean-Luc Vonesch
P304
P407
P577
2002-08-01T00:00:00Z