TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
about
UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytesMammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulinWnt signalling via the epidermal growth factor receptor: a role in breast cancer?ADAM metalloproteases and EGFR signallingG protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenuesCell-surface receptors transactivation mediated by g protein-coupled receptorsUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesHuman airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF alpha-converting enzyme activity in airway epithelial cellsCombinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processingADAMs: key components in EGFR signalling and developmentRegulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR systemAllograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophagesERBB receptors and cancer: the complexity of targeted inhibitorsIdentification of novel interaction between ADAM17 (a disintegrin and metalloprotease 17) and thioredoxin-1.A co-culture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells.Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligandsEctodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in miceSelective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor.Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genesActivated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction.ADAM-17: the enzyme that does it all.Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.Quantitative investigation of human cell surface N-glycoprotein dynamics.The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine modeTargeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivationTACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cellsEGFR may couple moderate alcohol consumption to increased breast cancer risk.Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.Functional microarray analysis suggests repressed cell-cell signaling and cell survival-related modules inhibit progression of head and neck squamous cell carcinomaAP-1 (Fra-1/c-Jun)-mediated induction of expression of matrix metalloproteinase-2 is required for 15S-hydroxyeicosatetraenoic acid-induced angiogenesis.Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionStimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways.Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal.Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat padConvergence between Wnt-β-catenin and EGFR signaling in cancer.Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735Glycoprotein capture and quantitative phosphoproteomics indicate coordinated regulation of cell migration upon lysophosphatidic acid stimulation.EGFR signaling in breast cancer: bad to the bone.
P2860
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P248
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P2860
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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name
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@ast
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en-gb
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@nl
type
label
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@ast
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en-gb
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@nl
prefLabel
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@ast
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en-gb
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
TACE cleavage of proamphiregul ...... n and motility of cancer cells
@en
P2093
Andreas Gschwind
Axel Ullrich
Oliver M Fischer
Stefan Hart
P2860
P304
P3181
P356
10.1093/EMBOJ/CDG231
P407
P577
2003-05-15T00:00:00Z