Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.
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Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulinEpidermal growth factor: a new therapeutic target in glomerular disease.A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous SystemsBinding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cellsHistone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteinsActive-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10Structure and function of epigen, the last EGFR ligand.ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.ADAM-17: the enzyme that does it all.The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine modeRoles for trafficking and O-linked glycosylation in the turnover of model cell surface proteins.Tumor necrosis factor-alpha converting enzyme: Implications for ocular inflammatory diseasesErbB/EGF signaling and EMT in mammary development and breast cancer.ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortexAmphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth.The ADAM17-amphiregulin-EGFR axis in mammary development and cancer.Transforming growth factor alpha (TGF-alpha) and other targets of tumor necrosis factor-alpha converting enzyme (TACE) in murine polycystic kidney disease.TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survivalTNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells.N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domainMitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metaboliteEpiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival.Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.Increased epidermal growth factor-like ligands are associated with elevated vascular nicotinamide adenine dinucleotide phosphate oxidase in a primate model of atherosclerosis.A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes.Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib.Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk.Molecular mechanisms of soluble cytokine receptor generation.Activator protein 2alpha mediates parathyroid TGF-alpha self-induction in secondary hyperparathyroidism.Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretaseADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.The role of protease activity in ErbB biology.Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.Neurogenesis and Alzheimer's disease: at the crossroads.Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortalityMechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity.New insights into ADAMs regulation of the GRO-α/CXCR2 system: focus on Sjögren's syndrome.Identification of cleavage sites leading to the shed form of the anti-aging protein klotho
P2860
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P2860
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Selective roles for tumor necr ...... etermines cleavage efficiency.
@ast
Selective roles for tumor necr ...... etermines cleavage efficiency.
@en
type
label
Selective roles for tumor necr ...... etermines cleavage efficiency.
@ast
Selective roles for tumor necr ...... etermines cleavage efficiency.
@en
prefLabel
Selective roles for tumor necr ...... etermines cleavage efficiency.
@ast
Selective roles for tumor necr ...... etermines cleavage efficiency.
@en
P2093
P2860
P356
P1476
Selective roles for tumor necr ...... etermines cleavage efficiency.
@en
P2093
C Leann Hinkle
Carol E Parker
David C Lee
David Loiselle
Mary Stevenson
William E Russell
P2860
P304
24179-24188
P356
10.1074/JBC.M312141200
P407
P577
2004-04-05T00:00:00Z