The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary
about
The biology of DHX9 and its potential as a therapeutic targetG-quadruplexes and helicasesG-quadruplexes and their regulatory roles in biologyOptimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex.A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1.DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formationRNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands.Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNAMutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and ProcessivityG-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction.Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis.Telomere lengthening and other functions of telomerase.Unzippers, resolvers and sensors: a structural and functional biochemistry tale of RNA helicasesThe tale of RNA G-quadruplex.RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3'-Tail of the Long Non-coding RNA BC200 (BCYRN1).RNA G-quadruplexes: emerging mechanisms in diseaseAven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.RNA G-quadruplexes and their potential regulatory roles in translation.Human DDX21 binds and unwinds RNA guanine quadruplexes.3' UTR G-quadruplexes regulate miRNA binding.Stimulation of ribosomal frameshifting by RNA G-quadruplex structures.Targeted Detection of G-Quadruplexes in Cellular RNAs.Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR.Specific features of telomerase RNA from Hansenula polymorpha.Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches.Structural Roles of Noncoding RNAs in the Heart of Enzymatic Complexes.On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids.Nanoscale Assembly of High-Mobility Group AT-Hook 2 Protein with DNA Replication Fork.Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration.Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase.Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
P2860
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P2860
The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@ast
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en-gb
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@nl
type
label
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@ast
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en-gb
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@nl
prefLabel
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@ast
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en-gb
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@nl
P2093
P2860
P50
P3181
P356
P1476
The RNA helicase RHAU (DHX36) ...... the P1 helix template boundary
@en
P2093
P2860
P304
P3181
P356
10.1093/NAR/GKR1306
P407
P577
2012-01-11T00:00:00Z