Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
about
The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundaryG4 resolvase 1 tightly binds and unwinds unimolecular G4-DNAp72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral proteinThe zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNAThe ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BRecruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domainG4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysatesRNA helicase proteins as chaperones and remodelersPost-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulationEvidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysatesMessenger RNA turnover in eukaryotes: pathways and enzymesAn integrated in silico approach to design specific inhibitors targeting human poly(a)-specific ribonucleaseHistone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcriptionPrimary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling networkADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins.Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAsInduction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells.Interaction of hnRNPA1/A2 and DAZAP1 with an Alu-derived intronic splicing enhancer regulates ATM aberrant splicingG-quadruplex nucleic acids and human diseaseIdentification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles.RNA helicases in infection and disease.RNA decay modulates gene expression and controls its fidelityA G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.Novel rapidly evolving hominid RNAs bind nuclear factor 90 and display tissue-restricted distributionThe RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1.Control of mRNA stability by SAPKs.DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formationSubstrate dependence of conformational changes in the RNA-binding domain of tristetraprolin assessed by fluorescence spectroscopy of tryptophan mutants.The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzymeMutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.The Protein Interaction of RNA Helicase B (RhlB) and Polynucleotide Phosphorylase (PNPase) Contributes to the Homeostatic Control of Cysteine in Escherichia coliRNA recognition by 3'-to-5' exonucleases: the substrate perspective.mRNA stability and cancer: an emerging link?Exosome-bound WD repeat protein Monad inhibits breast cancer cell invasion by degrading amphiregulin mRNAYTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex.Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).Inflammation: cytokines and RNA-based regulation.RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis.
P2860
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P248
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P2860
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
description
2004 nî lūn-bûn
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2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@ast
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@en
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@nl
type
label
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@ast
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@en
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@nl
prefLabel
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@ast
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@en
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@nl
P2093
P921
P3181
P1433
P1476
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
@en
P2093
Christiane Wirbelauer
Daniel Hess
Hoanh Tran
Yoshikuni Nagamine
P304
P3181
P356
10.1016/S1097-2765(03)00481-7
P407
P577
2004-01-01T00:00:00Z