The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
about
Rap2A links intestinal cell polarity to brush border formationRegulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentThe kinase TNIK is an essential activator of Wnt target genesAgonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingMINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor functionCrystal structure of the RUN domain of the RAP2-interacting protein xSignalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseConstitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction.A large-scale proteomic analysis of human embryonic stem cellsEmergence of TNIK inhibitors in cancer therapeutics.RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27.The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteinsRap1 and Rap2 antagonistically control endothelial barrier resistance.The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer.Rap2B promotes proliferation, migration, and invasion of human breast cancer through calcium-related ERK1/2 signaling pathway.Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathwayRap2B GTPase: structure, functions, and regulation.Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity.Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells.Structure, functional regulation and signaling properties of Rap2B.DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders.SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer.Rap2A Is Upregulated in Invasive Cells Dissected from Follicular Thyroid Cancer.Targeting the Wnt signaling pathway in colorectal cancer.Rap2a serves as a potential prognostic indicator of renal cell carcinoma and promotes its migration and invasion through up-regulating p-Akt.p53 target gene Rap2B regulates the cytoskeleton and inhibits cell spreading.Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.Enormous influence of TNIK knockdown on intracellular signals and cell survival.A null mutation in TNIK defines a novel locus for intellectual disability.Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration.Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK.Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A.Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase InhibitorNedd4 branches out.
P2860
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P2860
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@ast
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en-gb
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@nl
type
label
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@ast
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en-gb
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@nl
prefLabel
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@ast
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en-gb
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@nl
P2093
P2860
P921
P3181
P356
P1476
The Traf2- and Nck-interacting ...... to regulate actin cytoskeleton
@en
P2093
Bat-Erdene Myagmar
Hiroshi Uezato
Ken-ichi Kariya
Kimiko Takei
Kiyohito Taira
Manabu Shinzato
Masato Umikawa
Noriko Machida
Shigeo Nonaka
P2860
P304
P3181
P356
10.1074/JBC.M406370200
P407
P577
2004-11-19T00:00:00Z