TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
about
Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral developmentRegulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonCharacterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamilyActivation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRADIdentification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK betaDisrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophreniaInhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PESTThe kinase TNIK is an essential activator of Wnt target genesThe STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesionHuman Vam6p promotes lysosome clustering and fusion in vivoCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsAgonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingMAP4K4: an emerging therapeutic target in cancerDISC1-binding proteins in neural development, signalling and schizophreniaMINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor functionNESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesisIdentification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinaseDeficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytesNck adapter proteins: functional versatility in T cellsInduction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseThe Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors.Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction.Misshapen decreases integrin levels to promote epithelial motility and planar polarity in DrosophilaProteomics reveals multiple routes to the osteogenic phenotype in mesenchymal stem cellsA large-scale proteomic analysis of human embryonic stem cellsEmergence of TNIK inhibitors in cancer therapeutics.Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.Linking neurodevelopmental and synaptic theories of mental illness through DISC1Association between gene expression profiles and clinical outcome of pemetrexed-based treatment in patients with advanced non-squamous non-small cell lung cancer: exploratory results from a phase II study.MAL overexpression leads to disturbed expression of genes that influence cytoskeletal organization and differentiation of Schwann cells.The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strainsA genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved componentA Drosophila model of multiple endocrine neoplasia type 2.Rap1 and Rap2 antagonistically control endothelial barrier resistance.The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cellsCD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression
P2860
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P2860
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@ast
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en-gb
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@nl
type
label
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@ast
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en-gb
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@nl
prefLabel
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@ast
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en-gb
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@nl
P2093
P2860
P921
P3181
P356
P1476
TNIK, a novel member of the ge ...... and regulates the cytoskeleton
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.43.30729
P407
P577
1999-10-22T00:00:00Z