POT1 as a terminal transducer of TRF1 telomere length control
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityTIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentRap1 affects the length and heterogeneity of human telomeresPOT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyReplication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeresProtein requirements for sister telomere association in human cellsThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityWRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shorteningPOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationSIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinIn vivo stoichiometry of shelterin componentsIdentification of ATPases pontin and reptin as telomerase components essential for holoenzyme assemblyPurification of proteins associated with specific genomic LociTelomere protection by mammalian Pot1 requires interaction with Tpp1POT1 association with TRF2 regulates telomere lengthCharacterization of the DNA binding specificity of Shelterin complexesTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroPOT1 and TRF2 cooperate to maintain telomeric integrityPOT1 loss-of-function variants predispose to familial melanomaShelterin complex and associated factors at human telomeresRescue of an hTERT mutant defective in telomere elongation by fusion with hPot1Finding the end: recruitment of telomerase to telomeresTIN2-tethered TPP1 recruits human telomerase to telomeres in vivoFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationTelomere protection by TPP1 is mediated by POT1a and POT1bTelomere rapid deletion regulates telomere length in Arabidopsis thalianaA balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytesRegulating telomere length from the inside out: the replication fork modelTelomere and Telomerase Therapeutics in CancerMultiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic TargetsMultiple facets of TPP1 in telomere maintenanceMolecular regulation of telomerase activity in agingStructure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteinsStn1-Ten1 is an Rpa2-Rpa3-like complex at telomeresHow telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNACdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length Regulation
P2860
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
P248
Q21263027-7046A41D-4A12-43FC-B381-1DD7889B399FQ24292755-A23DCCB6-999F-4E00-A916-BCD920B1C4D0Q24293211-84EADFAA-1A3D-42F3-BA95-5BECC836C85EQ24298023-9E731978-D88E-4572-A0ED-6CCFE332EEFEQ24298357-BD9A6BE9-04F0-4F8E-BEFF-077849BF9499Q24298475-0327CA36-C474-471A-BB1F-3A8B576E73C3Q24298583-72A8E6EC-3586-4F78-9362-2F3C94ECF66FQ24298717-1E1D999E-6171-47C1-BCB8-5EC9AB2A4458Q24306780-EEC1A7F6-B9C1-4757-BE8F-CB6795589FD6Q24307499-728D2A03-DC28-49A9-A353-45FC661D90EEQ24308828-C24115CC-4609-4D11-82B0-4253159877D5Q24310189-0D885E4D-0F66-4D05-A325-A9A3E1CA532EQ24310658-7F9DFB68-CFE8-445B-B88F-315770B514A1Q24312021-DDE642EC-FC4F-498C-8FD0-B0B0FBF0CB11Q24313436-4DEEA7F5-3FE4-4CCF-8792-22534AA633BBQ24315634-E6548B3F-C0DE-41B2-B0FD-CEDA01C46BE7Q24319841-5C784A44-B0C8-4896-8F24-3395DD3ABB97Q24320254-FD334E74-136A-4E2D-AC57-664258A08BF2Q24323345-33F566A5-99D2-4468-A427-985609953EFAQ24336203-455F0FC2-84CC-48D7-9E9C-1C275D72990EQ24337394-12AF8270-07F8-43D0-99E4-8220BCE03C0BQ24338505-656CFF68-FF7E-47A2-A8FF-590DE27FADC3Q24563091-1DB88EED-DAB8-46DF-942E-EC2F759F90D0Q24601577-DADF2055-4049-42CD-8203-C8552B2CA4D4Q24603295-CB70B332-FF58-4C59-A0F1-BC67CFB96108Q24606549-CD5A8A6A-E010-4006-B7D1-03F8C3B0B96BQ24606587-FAB4A9EA-92A8-4F5D-A737-1AE414CC998BQ24607672-AA66FE21-AA43-4554-8BBA-ED31F74530B3Q24654732-EA10ECEB-DBCF-4B62-AC3F-B2D17FCE7A27Q24681584-0D349045-401F-4E8A-90EF-463DA2D32BD6Q25256930-EE0AAFF1-9436-439B-A637-B02187DC3B65Q26741230-0331C26F-612E-482F-9821-ABAAD984835FQ26744808-FEF05400-6751-4FB9-B210-F09E938D6BF6Q26795735-D0BBD5E4-184C-4546-8B1E-E0A70F5386E5Q26859063-A6066081-F3D8-4040-AD0A-875E2D737689Q26861714-57C73FF1-DF6B-418B-A2B1-7559E2B8FC39Q27650163-4E4C63EC-774B-4482-AE72-8BD0963BB08EQ27658652-2DBAB875-5D09-4489-9D74-75A8C921F3B5Q27659001-56B15A41-0926-4FFF-96FF-E27938FE94C6Q27664455-9CD83BEF-6FC9-43D6-9814-4F76CADED7C3
P2860
POT1 as a terminal transducer of TRF1 telomere length control
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
POT1 as a terminal transducer of TRF1 telomere length control
@ast
POT1 as a terminal transducer of TRF1 telomere length control
@en
POT1 as a terminal transducer of TRF1 telomere length control
@en-gb
POT1 as a terminal transducer of TRF1 telomere length control
@nl
type
label
POT1 as a terminal transducer of TRF1 telomere length control
@ast
POT1 as a terminal transducer of TRF1 telomere length control
@en
POT1 as a terminal transducer of TRF1 telomere length control
@en-gb
POT1 as a terminal transducer of TRF1 telomere length control
@nl
prefLabel
POT1 as a terminal transducer of TRF1 telomere length control
@ast
POT1 as a terminal transducer of TRF1 telomere length control
@en
POT1 as a terminal transducer of TRF1 telomere length control
@en-gb
POT1 as a terminal transducer of TRF1 telomere length control
@nl
P921
P3181
P356
P1433
P1476
POT1 as a terminal transducer of TRF1 telomere length control
@en
P2093
Diego Loayza
P2888
P304
P3181
P356
10.1038/NATURE01688
P407
P577
2003-06-26T00:00:00Z
P6179
1048894838