Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
about
The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapseAng2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complexThe fifth adaptor protein complexThe molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALMEARP is a multisubunit tethering complex involved in endocytic recyclingDecreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretaseAdaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short statureRole of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarityForty Years of Clathrin-coated VesiclesGolgi fragmentation in Alzheimer's diseaseThe clathrin adaptor complexes as a paradigm for membrane-associated allosteryLysosomal protein trafficking in Giardia lamblia: common and distinct featuresThe role of APP and BACE1 trafficking in APP processing and amyloid-β generationAdaptor protein complexes AP-4 and AP-5: new players in endosomal trafficking and progressive spastic paraplegiaStructures and mechanisms of vesicle coat components and multisubunit tethering complexesAlzheimer's disease--a panorama glimpseAxonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cellsVacuolar protein sorting mechanisms in plantsThe Amyloid Precursor Protein Controls PIKfyve FunctionCo-assembly of viral envelope glycoproteins regulates their polarized sorting in neuronsStructural Basis for the Recognition of Tyrosine-based Sorting Signals by the 3A Subunit of the AP-3 Adaptor ComplexStructural and Functional Characterization of Cargo-Binding Sites on the μ4-Subunit of Adaptor Protein Complex 4Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent StutteringStructural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 μ homology domainIdentification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid betaTetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent AutophagyMultivariate proteomic profiling identifies novel accessory proteins of coated vesiclesGenetic contributions to stuttering: the current evidence.Adaptor protein complexes and intracellular transport.AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteinsCalsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ productionCargo recognition in clathrin-mediated endocytosisSorting signals that mediate traffic of chitin synthase III between the TGN/endosomes and to the plasma membrane in yeast.Tissue-based Alzheimer gene expression markers-comparison of multiple machine learning approaches and investigation of redundancy in small biomarker setsCargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex.Molecular Basis for the Interaction Between AP4 β4 and its Accessory Protein, Tepsin.A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.A novel homozygous p.R1105X mutation of the AP4E1 gene in twins with hereditary spastic paraplegia and mycobacterial disease.
P2860
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P2860
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@ast
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en-gb
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@nl
type
label
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@ast
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en-gb
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@nl
altLabel
Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex
@en
prefLabel
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@ast
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en-gb
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@nl
P2093
P2860
P921
P3181
P1433
P1476
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex
@en
P2093
Gonzalo A Mardones
James H Hurley
Juan S Bonifacino
Luis L P daSilva
Patricia V Burgos
Yogikala Prabhu
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2010.01.015
P407
P577
2010-03-01T00:00:00Z