Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells
about
The role of NF-κB in the pathogenesis of gliomaOrder and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategiesMouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutationFrequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres.EGF receptor uses SOS1 to drive constitutive activation of NFκB in cancer cellsLPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophages.Shp2 plays an important role in acute cigarette smoke-mediated lung inflammationThe Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.NFKBIA deletion in glioblastomasIntegrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes.Molecular interactions of ErbB1 (EGFR) and integrin-β1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance.EGFR family: structure physiology signalling and therapeutic targets.Alternate paths from epidermal growth factor receptor to Akt in malignant versus nontransformed lung epithelial cells: ErbB3 versus Gab1.The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells.The NFκB pathway: a therapeutic target in glioblastoma.Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy.Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines.NF-κB inhibitor reverses temozolomide resistance in human glioma TR/U251 cells.Early clinical development of epidermal growth factor receptor targeted therapy in breast cancer.Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain CancerEffect of transforming growth factor Beta 1 on wound healing in induced diabetic rats.Looking in the miR-ror: TGF-β-mediated activation of NF-κB in glioma.Gab docking proteins in cardiovascular disease, cancer, and inflammation.Combined detection of Gab1 and Gab2 expression predicts clinical outcome of patients with glioma.SHP2 regulates proliferation and tumorigenicity of glioma stem cells.Activation of SHP2 through the binding to phospho-Gab1
P2860
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P2860
Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells
description
2004 nî lūn-bûn
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2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2004 թվականի հունվարին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@ast
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en-gb
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@nl
type
label
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@ast
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en-gb
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@nl
prefLabel
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@ast
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en-gb
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@nl
P2093
P2860
P1476
Distinct domains in the SHP-2 ...... ugh Gab1 in glioblastoma cells
@en
P2093
Gibbes R Johnson
Gurpreet S Kapoor
P2860
P304
P356
10.1128/MCB.24.2.823-836.2004
P407
P577
2004-01-01T00:00:00Z