POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308
about
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-linksPOLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cellsEvidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-linksA unique error signature for human DNA polymerase nuHuman DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitroDNA polymerase POLN participates in cross-link repair and homologous recombinationHigh-efficiency bypass of DNA damage by human DNA polymerase QDNA polymerase θ (POLQ), double-strand break repair, and cancerA nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycolDNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with AtmHow a homolog of high-fidelity replicases conducts mutagenic DNA synthesisHighly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I.Arabidopsis TEBICHI, with helicase and DNA polymerase domains, is required for regulated cell division and differentiation in meristems.DNA interstrand crosslink repair in mammalian cells: step by step.Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repairAnalysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activitySynthesis of site-specific DNA-protein conjugates and their effects on DNA replicationDNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instabilityMus308 processes oxygen and nitrogen ethylation DNA damage in germ cells of Drosophila.Human HEL308 localizes to damaged replication forks and unwinds lagging strand structuresKinetic analysis of the unique error signature of human DNA polymerase ν.Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidineHuman DNA polymerase θ grasps the primer terminus to mediate DNA repairHuman DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency.Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage.A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapyDNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses.Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).Linking DNA polymerase theta structure and function in health and diseaseDNA polymerase POLQ and cellular defense against DNA damage.Multiple functions of DNA polymerases.Low-fidelity DNA synthesis by human DNA polymerase theta.DNA polymerases and cancer.Helq acts in parallel to Fancc to suppress replication-associated genome instability.Structure-function analysis of DNA helicase HELQ: A new diagnostic marker in ovarian cancer.Translesion DNA synthesis in the context of cancer research.Mouse models of DNA polymerases.
P2860
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P2860
POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@ast
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en-gb
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@nl
type
label
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@ast
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en-gb
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@nl
prefLabel
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@ast
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en-gb
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@nl
P2860
P356
P1476
POLN, a nuclear PolA family DN ...... ink sensitivity protein Mus308
@en
P2093
Anthony Schuffert
P2860
P304
32014-32019
P356
10.1074/JBC.M305646200
P407
P577
2003-06-06T00:00:00Z