about
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.Inhibition of homologous recombination by the PCNA-interacting protein PARIFAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathwayBRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damageCtIP is required to initiate replication-dependent interstrand crosslink repairPOLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repairFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cellsMRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repairStructural basis for recruitment of BRCA2 by PALB2Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forksBreast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairPolyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehydeFunctional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatinStabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility proteinPALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility geneMolecular pathogenesis and clinical management of Fanconi anemiaMutations of the SLX4 gene in Fanconi anemiaSusceptibility pathways in Fanconi's anemia and breast cancerHow the fanconi anemia pathway guards the genomeATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expressionA human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group MBRCA mutations and childhood cancerA multiprotein nuclear complex connects Fanconi anemia and Bloom syndromeBRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarianFanconi anaemiaIdentification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repairFanconi anemia genes are highly expressed in primitive CD34+ hematopoietic cellsA novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancerAnalysis of baseline and cisplatin-inducible gene expression in Fanconi anemia cells using oligonucleotide-based microarrays.Mutation analysis of the ATR gene in breast and ovarian cancer families.Expression analysis of candidate breast tumour suppressor genes on chromosome 16qBACH1 Ser919Pro variant and breast cancer risk.The biological effects and clinical implications of BRCA mutations: where do we go from here?Mechanisms of interstrand DNA crosslink repair and human disordersA Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian Cancer Related to TumorigenesisPhenotypes and genotypes of the chromosomal instability syndromesInterplay between Fanconi anemia and homologous recombination pathways in genome integrity
P2860
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P1343
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Biallelic inactivation of BRCA2 in Fanconi anemia
@ast
Biallelic inactivation of BRCA2 in Fanconi anemia
@en
type
label
Biallelic inactivation of BRCA2 in Fanconi anemia
@ast
Biallelic inactivation of BRCA2 in Fanconi anemia
@en
prefLabel
Biallelic inactivation of BRCA2 in Fanconi anemia
@ast
Biallelic inactivation of BRCA2 in Fanconi anemia
@en
P2093
P4510
P3181
P356
P1433
P1476
Biallelic inactivation of BRCA2 in Fanconi anemia
@en
P2093
Alan D D'Andrea
Barbara Cox
Christine De Die-Smulders
Edward A Fox
Hans Joenje
Hideyuki Ikeda
Niall G Howlett
Nicole Persky
Quinten Waisfisz
Susan Olson
P304
P3181
P356
10.1126/SCIENCE.1073834
P407
P577
2002-06-13T00:00:00Z