HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome
about
J protein mutations and resulting proteostasis collapseThe ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1The UBL domain of PLIC-1 regulates aggresome formationBAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome systemDNAJs: more than substrate delivery to HSPAProtein quality control in the nucleusCo-chaperone HSJ1a dually regulates the proteasomal degradation of ataxin-3Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosisThe cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutantsMolecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutantCell line specific modulation of extracellular aβ42 by Hsp40BAG-6 is essential for selective elimination of defective proteasomal substratesUbe2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIPThe HSP70 chaperone machinery: J proteins as drivers of functional specificityPlasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shockHeat shock proteins: cellular and molecular mechanisms in the central nervous system.The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor TurnoverDNAJB2 expression in normal and diseased human and mouse skeletal muscle.Escorts take the lead molecular chaperones as therapeutic targetsSuppression of protein aggregation by chaperone modification of high molecular weight complexesEvaluation of the amyloid beta-GFP fusion protein as a model of amyloid beta peptides-mediated aggregation: a study of DNAJB6 chaperone.Cysteine string protein promotes proteasomal degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) by increasing its interaction with the C terminus of Hsp70-interacting protein and promoting CFTR ubiquitylation.Chaperoning erythropoiesis.Molecular chaperones and photoreceptor function.Chaperone-assisted degradation: multiple paths to destruction.CSPalpha: the neuroprotective J protein.Protein quality control at the plasma membrane.Protein homeostasis, aging and Alzheimer's disease.Opportunities and challenges for molecular chaperone modulation to treat protein-conformational brain diseasesThe role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channelsBarcoding heat shock proteins to human diseases: looking beyond the heat shock responseThe E3 ligase CHIP: insights into its structure and regulation.Chaperoning proteins for destruction: diverse roles of Hsp70 chaperones and their co-chaperones in targeting misfolded proteins to the proteasomeMolecular chaperones and neuronal proteostasis.Zebrafish as a Model for the Study of Chaperonopathies.Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain.RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology.A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation.When proteostasis goes bad: Protein aggregation in the cell.
P2860
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P2860
HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@ast
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en-gb
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@nl
type
label
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@ast
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en-gb
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@nl
prefLabel
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@ast
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en-gb
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@nl
P2093
P1433
P1476
HSJ1 is a neuronal shuttling f ...... rone clients to the proteasome
@en
P2093
Britta Westhoff
Jacqueline van der Spuy
Jörg Höhfeld
P304
P356
10.1016/J.CUB.2005.04.058
P407
P577
2005-06-01T00:00:00Z