Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis
about
Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentationBcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpointsPlk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionCalcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cellsRegulation of PTEN stability and activity by Plk3Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activityDynamic transcription programs during ES cell differentiation towards mesoderm in serum versus serum-freeBMP4 culture.Role of senescence and mitotic catastrophe in cancer therapy.The Golgi and the centrosome: building a functional partnership.Polo-box domain: a versatile mediator of polo-like kinase function.Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemiaThe structural basis of localizing polo-like kinase to the flagellum attachment zone in Trypanosoma brucei.Osmotic stress-induced phosphorylation of H2AX by polo-like kinase 3 affects cell cycle progression in human corneal epithelial cellsEffect of hypoxic stress-activated Polo-like kinase 3 on corneal epithelial wound healingAttenuated monocyte apoptosis, a new mechanism for osteoporosis suggested by a transcriptome-wide expression study of monocytesTargeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer TreatmentActivation of Polo-like kinase 3 by hypoxic stresses.Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions.Cytoskeletal architecture and cell motility remain unperturbed in mouse embryonic fibroblasts from Plk3 knockout mice.ER-Golgi network--a future target for anti-cancer therapy.The role of Plk3 in oncogenesis.Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8.Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.Activity-induced Polo-like kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity.Site-specific promoter caging enables optochemical gene activation in cells and animals.
P2860
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P2860
Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@ast
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en-gb
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@nl
type
label
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@ast
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en-gb
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@nl
prefLabel
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@ast
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en-gb
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@nl
P2093
P2860
P921
P3181
P356
P1476
Polo box domain of Plk3 functi ...... kinesis defects, and apoptosis
@en
P2093
Meena Jhanwar-Uniyal
Ning Jiang
Xiaoxing Wang
P2860
P304
P3181
P356
10.1074/JBC.M513156200
P407
P577
2006-04-14T00:00:00Z