Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas
about
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alphaCalcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progressionPolo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosisHyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cellsCalcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cellsCell cycle arrest and apoptosis induced by human Polo-like kinase 3 is mediated through perturbation of microtubule integrityPlk phosphorylation regulates the microtubule-stabilizing protein TCTP.Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cellsEssential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures.The physical association and phosphorylation of Cdc25C protein phosphatase by PrkPRK, a cell cycle gene localized to 8p21, is downregulated in head and neck cancerMammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathwaysPlk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathwayHuman Prk is a conserved protein serine/threonine kinase involved in regulating M phase functionsRegulation of PTEN stability and activity by Plk3Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation.Phosphorylation of synucleins by members of the Polo-like kinase family.Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice.Polo-box domain: a versatile mediator of polo-like kinase function.The structural basis of localizing polo-like kinase to the flagellum attachment zone in Trypanosoma brucei.Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase.Identification of the human homologue of the early-growth response gene Snk, encoding a serum-inducible kinase.Hormonal induction of polo-like kinases (Plks) and impact of Plk2 on cell cycle progression in the rat ovary.Osmotic stress-induced phosphorylation of H2AX by polo-like kinase 3 affects cell cycle progression in human corneal epithelial cellsPolo-like kinases and centrosome regulation.Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun.Molecular genetic study of novel biomarkers for early diagnosis of oral squamous cell carcinomaDysregulation of the polo-like kinase pathway in CD4+ T cells is characteristic of pathogenic simian immunodeficiency virus infection.From Plk1 to Plk5: functional evolution of polo-like kinasesTargeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer TreatmentPolo-like kinases, an introduction.Regulation of cell cycle checkpoints by polo-like kinases.The Plk3-Cdc25 circuit.Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk.Recent Advances and New Strategies in Targeting Plk1 for Anticancer TherapyPlk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structuresThe polo-box-dependent induction of ectopic septal structures by a mammalian polo kinase, plk, in Saccharomyces cerevisiae.Activation of Polo-like kinase 3 by hypoxic stresses.Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions.
P2860
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P2860
Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas
description
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im August 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/08/09)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/08/09)
@nl
наукова стаття, опублікована в серпні 1996
@uk
name
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@ast
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@en
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@nl
type
label
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@ast
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@en
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@nl
prefLabel
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@ast
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@en
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@nl
P2093
P2860
P3181
P356
P1476
Prk, a cytokine-inducible huma ...... n-regulated in lung carcinomas
@en
P2093
D. J. Slamon
P. T. Reissmann
P2860
P304
19402–19408
P3181
P356
10.1074/JBC.271.32.19402
P407
P577
1996-08-09T00:00:00Z