Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction
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The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth diseaseCore protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complexMyotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activityPIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell deathPIKfyve: Partners, significance, debates and paradoxesArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytesThe Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnoverSkeletal Muscle Pathology in X-Linked Myotubular Myopathy: Review With Cross-Species ComparisonsCharcot-Marie-Tooth disease and intracellular trafficLoss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathyMTM-6, a phosphoinositide phosphatase, is required to promote synapse formation in Caenorhabditis elegansPhosphoinositide regulation of integrin trafficking required for muscle attachment and maintenanceCaenorhabditis elegans myotubularin MTM-1 negatively regulates the engulfment of apoptotic cellsStructure of the catalytic phosphatase domain of MTMR8: implications for dimerization, membrane association and reversible oxidationLocalized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusionAAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasisMulti-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domainTargeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Zebrafish MTMR14 is required for excitation-contraction coupling, developmental motor function and the regulation of autophagy.Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathwaysMultiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.Cooperation of Mtmr8 with PI3K regulates actin filament modeling and muscle development in zebrafishDrosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functionsMembrane traffic and muscle: lessons from human diseaseExpression, purification, crystallization and preliminary crystallographic analysis of human myotubularin-related protein 3Crystallization and preliminary X-ray crystallographic analysis of the PH-GRAM domain of human MTMR4Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cellsPhosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels.Activity-dependent PI(3,5)P2 synthesis controls AMPA receptor trafficking during synaptic depression.Endplate structure and parameters of neuromuscular transmission in sporadic centronuclear myopathy associated with myasthenia.Identification and phylogenetic analyses of VASt, an uncharacterized protein domain associated with lipid-binding domains in Eukaryotes.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.The myotubularin family of lipid phosphatases in disease and in spermatogenesisMyotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotypePtdIns5P: news and views of its appearance, disappearance and deeds.Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8.
P2860
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P2860
Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction
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2004 nî lūn-bûn
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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2004 թվականի ապրիլին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@ast
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en-gb
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@nl
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label
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@ast
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en-gb
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@nl
prefLabel
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@ast
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en-gb
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
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P2093
P50
P356
P1476
Myotubularin regulates the fun ...... l 3,5-bisphosphate interaction
@en
P2093
Akitsugu Yamamoto
Kazuya Tsujita
Tadaomi Takenawa
Toshiki Itoh
P304
P356
10.1074/JBC.M312294200
P407
P577
2004-04-02T00:00:00Z