The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
about
Mutations in PTF1A cause pancreatic and cerebellar agenesisHepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in micePTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentIncreased islet apoptosis in Pdx1+/- miceNotch Signaling in Pancreatic DevelopmentDevelopmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginRecent developments in β-cell differentiation of pluripotent stem cells induced by small and large moleculesMouse models of pancreatic cancerPancreatic ductal cells in development, regeneration, and neoplasiaPancreas-specific Cre driver lines and considerations for their prudent useElimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in miceImaging proteolytic activity in live cells and animal modelsGenetic dissection of the function of hindbrain axonal commissuresNatural history of β-cell adaptation and failure in type 2 diabetesUtilizing past and present mouse systems to engineer more relevant pancreatic cancer modelsTranscription factor regulation of pancreatic organogenesis, differentiation and maturationOncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesisDirected pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factorspdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasisGata6 is an important regulator of mouse pancreas developmentDynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformationPtf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanismPtf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous systemA dosage-dependent requirement for Sox9 in pancreatic endocrine cell formationThe nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesisNkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic isletSox17 regulates organ lineage segregation of ventral foregut progenitor cellsEGF receptor is required for KRAS-induced pancreatic tumorigenesisGenome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticityDelta-like 1 regulates Bergmann glial monolayer formation during cerebellar developmentInhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasiaHnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreasRNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factorsPrdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuitsEarly pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complexMammalian COPII coat component SEC24C is required for embryonic development in miceTargeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies.Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy.
P2860
Q24314872-33AFA994-7084-4781-8E33-7B7F3DB56393Q24531523-29A46584-5A3B-4260-9309-43D30B4AB4A9Q24535567-33840FA3-1840-47D7-9FCF-E8FC81071B66Q24682440-15ECE613-2B76-4DC1-854A-5D4DF4F4F3F7Q24683719-AB20C0DE-9422-470C-9A51-FC839163ADEBQ26771258-B9058433-2BEF-4F3C-8C12-AA74071CBA33Q26774942-33F40CD6-544E-4FAB-9B8A-418C95FFDA47Q26825664-FD51218E-423D-4586-89E2-2A9B76B7A840Q26860574-FECEB119-92CE-4FE8-BF16-23C51DC875A0Q27006729-0FD3FA47-CC7E-4606-AF28-7888D309D3E0Q27011305-D80FB22D-E6C3-4B52-BA16-82E58D809DCBQ27309018-45624323-1470-4FC7-B8E4-837B59667EE0Q27314960-897CC17C-C93A-409E-9A49-DFFE5C358744Q27324810-884FDE04-E3C4-4747-87A8-C3A89D94DC4BQ28082002-ECDFB4CC-429F-4975-8903-96EF9A1E772FQ28083091-FF9CC40F-A259-4464-AC00-9D760C9446A9Q28083955-8CAED4FE-5C4B-4279-98B6-838EB05140FDQ28242612-3B449470-A255-453E-8DAE-292795E4E23CQ28485172-C0E7DF19-BCD2-4290-BBE5-3A884B529BBAQ28504532-441B70F1-E626-486E-BE86-B4DF1FD43866Q28505084-4EB386C8-BCAB-41EF-9079-4E2A68D880CDQ28507165-15F3134D-7F2C-47F2-BF03-7AAE8ED35F93Q28508691-C03B11E5-0A79-4548-AE03-216A68734AB0Q28509708-E37622A7-53B3-436A-A3DA-F172D3802DC4Q28510770-44D753B4-996A-410B-BB3B-9CB99FED7F26Q28511736-6A0FBF2B-DF46-4AC2-9A7F-35096E36E368Q28512983-AD4717D9-54FC-42E8-B61D-956D7E010869Q28513551-CD236D91-B9CC-46B7-A080-7E45C3B42928Q28584901-DDBA9B8B-840B-4A88-A95B-432C4A2C7B5AQ28586286-8B168BEB-107E-4791-A58E-510AE06CCAEEQ28587949-11F887DE-1AF5-40F5-8836-ABDD7501FBC2Q28589628-E2288E9A-8BA0-41F5-BA58-33C68A2AB118Q28590347-9590C02F-EDC7-493C-B628-B9C310826AD1Q28591095-B50CF149-61B7-4CD6-9DF6-01FEF57E91FFQ28591563-E83A3BBE-214D-4097-9B79-0F0130A416C9Q28593332-77373DE5-D26D-404F-B2E8-043EB5342C1FQ28593531-3D7AB580-2F6C-43AA-AC1F-F1EEA5BC114BQ28593881-941172E1-7846-41ED-987D-6ABCC7FB38FEQ30386750-9889DE4D-6FE6-420A-AD32-8A707C4B2D7DQ30388746-F6FAD86F-04C0-4FC6-9D7B-F5ED242DFBF4
P2860
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The role of the transcriptiona ...... inal to pancreatic progenitors
@ast
The role of the transcriptiona ...... inal to pancreatic progenitors
@en
The role of the transcriptiona ...... inal to pancreatic progenitors
@en-gb
The role of the transcriptiona ...... inal to pancreatic progenitors
@nl
type
label
The role of the transcriptiona ...... inal to pancreatic progenitors
@ast
The role of the transcriptiona ...... inal to pancreatic progenitors
@en
The role of the transcriptiona ...... inal to pancreatic progenitors
@en-gb
The role of the transcriptiona ...... inal to pancreatic progenitors
@nl
prefLabel
The role of the transcriptiona ...... inal to pancreatic progenitors
@ast
The role of the transcriptiona ...... inal to pancreatic progenitors
@en
The role of the transcriptiona ...... inal to pancreatic progenitors
@en-gb
The role of the transcriptiona ...... inal to pancreatic progenitors
@nl
P2093
P3181
P356
P1433
P1476
The role of the transcriptiona ...... inal to pancreatic progenitors
@en
P2093
Bonnie Cooper
Christopher V E Wright
Maureen Gannon
Michael Ray
Raymond J MacDonald
Yoshiya Kawaguchi
P2888
P304
P3181
P356
10.1038/NG959
P407
P577
2002-09-01T00:00:00Z
P6179
1041398021