Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer

Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer

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http://www.wikidata.org/entity/Q24305235
NAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cellsRegulating the 20S proteasome ubiquitin-independent degradation pathway.Mitochondrial function in human neuroblastoma cells is up-regulated and protected by NQO1, a plasma membrane redox enzyme.NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation.Pathway Regulation of p63, a Director of Epithelial Cell FateInduction of NAD(P)H-quinone oxidoreductase 1 by antioxidants in female ACI rats is associated with decrease in oxidative DNA damage and inhibition of estrogen-induced breast cancer.Topical hesperidin improves epidermal permeability barrier function and epidermal differentiation in normal murine skin.NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice.NAD(P)H:quinone oxidoreductase 1 (NQO1) competes with 20S proteasome for binding with C/EBPα leading to its stabilization and protection against radiation-induced myeloproliferative disease.Genome-wide analysis of long noncoding RNA (lncRNA) expression in colorectal cancer tissues from patients with liver metastasis.NRH:quinone oxidoreductase 2 (NQO2) protein competes with the 20 S proteasome to stabilize transcription factor CCAAT enhancer-binding protein α (C/EBPα), leading to protection against γ radiation-induced myeloproliferative disease.NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.miR-205 regulates basement membrane deposition in human prostate: implications for cancer development.Control of stability of cyclin D1 by quinone reductase 2 in CWR22Rv1 prostate cancer cells.Stress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer.NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A.
P2860

Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer

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http://www.wikidata.org/entity/Q24305235
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@ast
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@en-gb
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@ast
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@en
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@en-gb
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@nl
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@ast
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
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Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
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P1433
P1476
P2093
P2860
P2888
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P6179
P698
P932
P3181
P356
P1433
P1476
Disruption of NAD(P)H:quinone ...... d chemical-induced skin cancer
@en
P2093
P2860
P2888
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P6179
P698
P932