NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms
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Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancerEffects of redox cycling compounds on DT diaphorase activity in the liver of rainbow trout (Oncorhynchus mykiss)New Therapeutic Concept of NAD Redox Balance for Cisplatin NephrotoxicityImplications of NQO1 in cancer therapyModulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy.Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification.Balkan endemic nephropathy: an update on its aetiologyNQO1 C609T polymorphism and colorectal cancer susceptibility: a meta-analysisNAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotectorThe NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysisNuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defensesInduction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and eAn NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancerWrbA from Escherichia coli and Archaeoglobus fulgidus is an NAD(P)H:quinone oxidoreductaseAir pollution and circulating biomarkers of oxidative stressFeatures of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex INovel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosisMolecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cellsVariation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment.Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity.Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice.Clinicopathological implications of NQO1 overexpression in the prognosis of pancreatic adenocarcinoma.Synthesis, metabolism and in vitro cytotoxicity studies on novel lavendamycin antitumor agents.Downregulation of NAD(P)H:quinone oxidoreductase 1 inhibits proliferation, cell cycle and migration of cholangiocarcinoma cells.Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injuryEffects of acupuncture at Taixi acupoint (KI3) on kidney proteome.A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.Nocardiopsis species: a potential source of bioactive compounds.Clinical significance of NQO1 polymorphism and expression of p53, SOD2, PARP1 in limited-stage small cell lung cancerTranscriptome and allele specificity associated with a 3BL locus for Fusarium crown rot resistance in bread wheat.NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review.A new approach for pharmacokinetic studies of natural products: measurement of isoliquiritigenin levels in mice plasma, urine and feces using modified automated dosing/blood sampling system.Functional study of the vitamin K cycle in mammalian cells.NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomasHuman aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact.Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.Differential responses of targeted lung redox enzymes to rat exposure to 60 or 85% oxygen.
P2860
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P2860
NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@ast
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@en
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
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type
label
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@ast
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@en
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@nl
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NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@ast
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@en
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
@nl
P2093
P3181
P1476
NAD(P)H:quinone oxidoreductase ...... tion and genetic polymorphisms
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P2093
P3181
P356
10.1016/S0009-2797(00)00199-X
P407
P577
2000-12-01T00:00:00Z