Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis - Wikidata - awgldk - TriplyDB

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

http://www.wikidata.org/entity/Q24305561

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betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21 FGF21 N- and C-termini play different roles in receptor interaction and activation Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis Chronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 release FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids Endocrine fibroblast growth factors 15/19 and 21: from feast to famine The role of bile after Roux-en-Y gastric bypass in promoting weight loss and improving glycaemic control Bile acids: regulation of apoptosis by ursodeoxycholic acid Bile acids: regulation of synthesis Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation Role of bile acids in the regulation of the metabolic pathways Novel bile acid therapeutics for the treatment of chronic liver diseases Fibroblast Growth Factor Signaling in Metabolic Regulation Bile acid receptors and nonalcoholic fatty liver disease Mechanism Underlying the Weight Loss and Complications of Roux-en-Y Gastric Bypass. Review Bile acid metabolism and signaling FXR signaling in the enterohepatic system Bile acids, obesity, and the metabolic syndrome Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis Cross-talk between bile acids and intestinal microbiota in host metabolism and health Genomic instability in liver cells caused by an LPS-induced bystander-like effect Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1 Genetic insights into the mechanisms of Fgf signaling Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21 Bile acid nuclear receptor FXR and digestive system diseases The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity Bile acid signaling in metabolic disease and drug therapy Review article: bile acid diarrhoea - pathogenesis, diagnosis and management Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element Farnesoid X receptor is essential for normal glucose homeostasis Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.

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P2860

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

http://www.wikidata.org/entity/Q24305561

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Genes & Development

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Definition of a novel growth f ...... sion of bile acid biosynthesis

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Bryan Goodwin

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Da Yuan Wang

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Guizhen Luo

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Jason A Holt

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John Bisi

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Karen F Kozarsky

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Mary Donahee

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Stacey A Jones

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Steven A Kliewer

http://www.w3.org/2001/XMLSchema#string

Traci A Mansfield

http://www.w3.org/2001/XMLSchema#string

P2860

Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

Fibroblast growth factors

FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene

A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice

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1581-91

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scholarly article

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2114592

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10.1101/GAD.1083503

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13

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2003-07-01T00:00:00Z

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12815072

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Nuclear receptor subfamily 1 group H member 4

sequence-specific DNA binding

Fibroblast growth factor 19

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196131

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