Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis
about
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivationBile acids: regulation of synthesisStructural insights into gene repression by the orphan nuclear receptor SHPRole of farnesoid X receptor and bile acids in alcoholic liver diseaseANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cellsGPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor αSUMOylation of GPS2 protein regulates its transcription-suppressing function.Nuclear receptor corepressor complexes in cancer: mechanism, function and regulationRegulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modificationsGPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication.The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor γ requires G protein pathway suppressor 2.Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partnerStructural basis for corepressor assembly by the orphan nuclear receptor TLX.Bile Acids as Hormones: The FXR-FGF15/19 PathwayExchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo.Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- miceFXR an emerging therapeutic target for the treatment of atherosclerosisFarnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice.G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.Role of farnesoid X receptor in inflammation and resolution.Role of farnesoid X receptor in cholestasis.Intestinal bile acid receptors are key regulators of glucose homeostasis.A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.Differential regulation of bile acid and cholesterol metabolism by the farnesoid X receptor in Ldlr -/- mice versus hamsters.E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesisSystemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue.The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ.A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic bone: the role of aryl hydrocarbon receptor as a mediator of osteogenic action.Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development.Transcriptional repression in macrophages-basic mechanisms and alterations in metabolic inflammatory diseases.Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration
P2860
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P2860
Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Involvement of corepressor com ...... g human bile acid biosynthesis
@ast
Involvement of corepressor com ...... g human bile acid biosynthesis
@en
Involvement of corepressor com ...... g human bile acid biosynthesis
@nl
type
label
Involvement of corepressor com ...... g human bile acid biosynthesis
@ast
Involvement of corepressor com ...... g human bile acid biosynthesis
@en
Involvement of corepressor com ...... g human bile acid biosynthesis
@nl
prefLabel
Involvement of corepressor com ...... g human bile acid biosynthesis
@ast
Involvement of corepressor com ...... g human bile acid biosynthesis
@en
Involvement of corepressor com ...... g human bile acid biosynthesis
@nl
P2093
P2860
P50
P356
P1476
Involvement of corepressor com ...... g human bile acid biosynthesis
@en
P2093
Ann Båvner
Anna Haroniti
Curt Einarsson
Eckardt Treuter
Lisa-Mari Nilsson
Michael Robin Witt
Stefan Rehnmark
Thomas Lundåsen
P2860
P304
P356
10.1073/PNAS.0706736104
P407
P577
2007-10-02T00:00:00Z