Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc
about
Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as MetalloproteinsExtracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulationSolution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells.Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsCloning and characterization of a P2X receptor expressed in the central nervous system of Lymnaea stagnalisIdentification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains.Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor.The mechanism by which ethanol inhibits rat P2X4 receptors is altered by mutation of histidine 241.Activation and regulation of purinergic P2X receptor channelsCalcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion.Allosteric modulation of ATP-gated P2X receptor channelsHeteromeric assembly of P2X subunits.Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum.Purinergic regulation of cholangiocyte secretion: identification of a novel role for P2X receptors.A P2X7 receptor stimulates plasma membrane trafficking in the FRTL rat thyrocyte cell line.Distinct purinergic signaling pathways in prepubescent mouse spermatogonia.Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region.Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition.P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation.
P2860
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P2860
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@ast
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en-gb
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@nl
type
label
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@ast
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en-gb
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@nl
prefLabel
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@ast
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en-gb
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@nl
P2093
P2860
P3181
P356
P1476
Histidine 140 plays a key role ...... eceptor by copper but not zinc
@en
P2093
Bernardo Morales
Claudio Coddou
Felipe Gordillo
Francois Rassendren
J Pablo Huidobro-Toro
Jorge González
Marta Grauso
Paulina Bull
P2860
P304
P3181
P356
10.1074/JBC.M305177200
P407
P577
2003-09-19T00:00:00Z