Zinc and copper modulate differentially the P2X4 receptor
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Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zincZinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as MetalloproteinsExtracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulationSolution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.Molecular characterization and expression analysis of ATP-gated P2X7 receptor involved in Japanese flounder (Paralichthys olivaceus) innate immune response.P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsStructural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.Identification of P2X₃ and P2X₇ purinergic receptors activated by ATP in rat lacrimal glandActivation and regulation of purinergic P2X receptor channelsGlutamate-mediated primary somatosensory cortex excitability correlated with circulating copper and ceruloplasminAllosteric modulation of ATP-gated P2X receptor channelsCadmium and its neurotoxic effectsExtracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targetsP2X(7) receptor at the heart of disease.Molecular Structure and Regulation of P2X Receptors With a Special Emphasis on the Role of P2X2 in the Auditory System.The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors.Intracellular calcium measurements as a method in studies on activity of purinergic P2X receptor channels.Modulation of ATP-induced currents by zinc in acutely isolated hypothalamic neurons of the rat.Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region.Analysis of macroscopic ionic currents mediated by GABArho1 receptors during lanthanide modulation predicts novel states controlling channel gating.Extracellular ATP and zinc are co-secreted with insulin and activate multiple P2X purinergic receptor channels expressed by islet beta-cells to potentiate insulin secretion.The role of histidine residues in modulation of the rat P2X(2) purinoceptor by zinc and pH.Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.The hypolipidemic drug metabolites nafenopin-CoA and ciprofibroyl-CoA are competitive P2Y1 receptor antagonists.Neocuproine, a copper (I) chelator, potentiates purinergic component of vas deferens contractions elicited by electrical field stimulation.Copper Signaling in the Brain and Beyond.Purinergic receptors in human placenta: evidence for functionally active P2X4, P2X7, P2Y2, and P2Y6.Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition.The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease.P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation.Divalent metal modulation of Japanese flounder (Paralichthys olivaceus) purinergic P2X7 receptor.Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel.
P2860
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P2860
Zinc and copper modulate differentially the P2X4 receptor
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Zinc and copper modulate differentially the P2X4 receptor
@ast
Zinc and copper modulate differentially the P2X4 receptor
@en
Zinc and copper modulate differentially the P2X4 receptor
@nl
type
label
Zinc and copper modulate differentially the P2X4 receptor
@ast
Zinc and copper modulate differentially the P2X4 receptor
@en
Zinc and copper modulate differentially the P2X4 receptor
@nl
prefLabel
Zinc and copper modulate differentially the P2X4 receptor
@ast
Zinc and copper modulate differentially the P2X4 receptor
@en
Zinc and copper modulate differentially the P2X4 receptor
@nl
P3181
P1476
Zinc and copper modulate differentially the P2X4 receptor
@en
P2093
J P Huidobro-Toro
P304
P3181
P356
10.1046/J.1471-4159.2000.0741529.X
P407
P577
2000-04-01T00:00:00Z