Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors
about
Targeting cancer with kinase inhibitorsNilotinib in patients with systemic mastocytosis: analysis of the phase 2, open-label, single-arm nilotinib registration studyExpression of proto-oncogene KIT is up-regulated in subset of human meningiomasScreening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models.Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.Duodenal gangliocytic paraganglioma: report of two cases and review of literature.Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.Implication of tumor microenvironment in chemoresistance: tumor-associated stromal cells protect tumor cells from cell death.The Role of Mast Cells in Molding the Tumor Microenvironment.The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer.Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies.CD117 expression in breast phyllodes tumors correlates with adverse pathologic parameters and reduced survival.Mast cell deficiency attenuates acupuncture analgesia for mechanical pain using c-kit gene mutant rats.In cancer cell lines inhibition of SCF/c-Kit pathway leads to radiosensitization only when SCF is strongly over-expressed.
P2860
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P2860
Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@ast
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en-gb
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@nl
type
label
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@ast
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en-gb
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@nl
prefLabel
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@ast
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en-gb
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@nl
P2093
P2860
P921
P356
P1433
P1476
Tumor-intrinsic and -extrinsic ...... of tyrosine kinase inhibitors
@en
P2093
M P Colombo
S Piconese
P2860
P2888
P304
P356
10.1038/ONC.2010.494
P407
P577
2011-02-17T00:00:00Z
P5875
P6179
1042151413