Structural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinases
about
Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitorsMechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cellsStructure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinasesCell signaling by receptor tyrosine kinasesStructures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complexClass III Receptor Tyrosine Kinases in Acute Leukemia - Biological Functions and Modern Laboratory AnalysisMultipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complexThe mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal regionMutation D816V alters the internal structure and dynamics of c-KIT receptor cytoplasmic region: implications for dimerization and activation mechanismsStructure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy.Spatial distribution and receptor specificity of zebrafish Kit system--evidence for a Kit-mediated bi-directional communication system in the preovulatory ovarian follicleFull-length recombinant human SCF1-165 is more thermostable than the truncated SCF1-141 form.Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles.Residues 39-56 of Stem Cell Factor Protein Sequence Are Capable of Stimulating the Expansion of Cord Blood CD34+ Cells.Structure-based view of epidermal growth factor receptor regulation.Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers.Platelet-derived growth factors and their receptors: structural and functional perspectives.Interstitial Cells of Cajal: Pathology, injury and repair.Tropomyosin-receptor-kinases signaling in the nervous system.The SCF/c-KIT system in the male: Survival strategies in fertility and cancer.The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer.Hypoxia and MITF regulate KIT oncogenic properties in melanocytes.Cloning of Soluble Human Stem Cell Factor in pET-26b(+) Vector.Microarray profiling of gene expression in human keratinocytes suggests a new protective activity against UV-induced DNA damage for a compound previously known to interact with SCF-KIT signalling pathway.Genetic variation at KIT locus may predispose to melanoma.Dimerization of KIT upon SCF bindingScreening for key lncRNAs in the progression of gallbladder cancer using bioinformatics analyses.Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.Molecular analysis of WT1 and KIT mutations in patients from an Indian population with de novo acute myeloid leukemia: determination of incidence, distribution patterns, and report of a novel KIT mutation.In cancer cell lines inhibition of SCF/c-Kit pathway leads to radiosensitization only when SCF is strongly over-expressed.KITand melanoma predisposition in pigs: sequence variants and association analysis
P2860
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P2860
Structural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinases
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural basis for stem cell ...... III receptor tyrosine kinases
@ast
Structural basis for stem cell ...... III receptor tyrosine kinases
@en
Structural basis for stem cell ...... III receptor tyrosine kinases
@nl
type
label
Structural basis for stem cell ...... III receptor tyrosine kinases
@ast
Structural basis for stem cell ...... III receptor tyrosine kinases
@en
Structural basis for stem cell ...... III receptor tyrosine kinases
@nl
prefLabel
Structural basis for stem cell ...... III receptor tyrosine kinases
@ast
Structural basis for stem cell ...... III receptor tyrosine kinases
@en
Structural basis for stem cell ...... III receptor tyrosine kinases
@nl
P2093
P2860
P356
P1433
P1476
Structural basis for stem cell ...... III receptor tyrosine kinases
@en
P2093
Pamela J Focia
Xiaolin He
Xiaoyan Chen
P2860
P304
P356
10.1038/SJ.EMBOJ.7601545
P407
P577
2007-02-07T00:00:00Z