A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2
about
A potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.Functional analysis of mutations in TGIF associated with holoprosencephaly.Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their CrosstalksAnalysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathwaysFoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestineGLI2 regulates TGF-β1 in human CD4+ T cells: implications in cancer and HIV pathogenesis.Single median maxillary central incisor: new data and mutation review.Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.Current recommendations for the molecular evaluation of newly diagnosed holoprosencephaly patientsThe molecular genetics of holoprosencephaly.Analysis of genotype-phenotype correlations in human holoprosencephaly.Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent stateAbnormal sterol metabolism in holoprosencephalypiggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasiaCis-regulatory control of human GLI2 expression in the developing neural tube and limb bud.Repurposing the antihelmintic mebendazole as a hedgehog inhibitor.Clinical findings in patients with GLI2 mutations--phenotypic variability.The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.Hedgehog/Ras interactions regulate early stages of pancreatic cancer.Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.Utilizing prospective sequence analysis of SHH, ZIC2, SIX3 and TGIF in holoprosencephaly probands to describe the parameters limiting the observed frequency of mutant gene×gene interactionsA shift in anterior-posterior positional information underlies the fin-to-limb evolution.Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.Comparison of mutation findings in ZIC2 between microform and classical holoprosencephaly in a Brazilian cohortSonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons.Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder.Functional characterization of a heterozygous GLI2 missense mutation in patients with multiple pituitary hormone deficiency.HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cellsOsteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.Sonic Hedgehog Signaling and VACTERL Association.Missense substitutions in the GAS1 protein present in holoprosencephaly patients reduce the affinity for its ligand, SHH.
P2860
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P2860
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A previously unidentified amin ...... disease-associated human GLI2
@ast
A previously unidentified amin ...... disease-associated human GLI2
@en
A previously unidentified amin ...... disease-associated human GLI2
@en-gb
A previously unidentified amin ...... disease-associated human GLI2
@nl
type
label
A previously unidentified amin ...... disease-associated human GLI2
@ast
A previously unidentified amin ...... disease-associated human GLI2
@en
A previously unidentified amin ...... disease-associated human GLI2
@en-gb
A previously unidentified amin ...... disease-associated human GLI2
@nl
prefLabel
A previously unidentified amin ...... disease-associated human GLI2
@ast
A previously unidentified amin ...... disease-associated human GLI2
@en
A previously unidentified amin ...... disease-associated human GLI2
@en-gb
A previously unidentified amin ...... disease-associated human GLI2
@nl
P2093
P3181
P356
P1476
A previously unidentified amin ...... disease-associated human GLI2
@en
P2093
Aiqin Wang
Alexandre N Ermilov
Andrzej A Dlugosz
Dorothy Katherine Grange
Erich Roessler
Marina Grachtchouk
Maximilian Muenke
P304
P3181
P356
10.1093/HMG/DDI222
P407
P577
2005-08-01T00:00:00Z